Radiation-induced bystander effects: past history and future directions

C Mothersill, C Seymour - Radiation research, 2001 - meridian.allenpress.com
Abstract Mothersill, C. and Seymour, C. Radiation-Induced Bystander Effects: Past History
and Future Directions. Radiat. Res. 155, 757–765 (2001). There has been a recent upsurge …

Mechanism of radiation-induced bystander effects: a unifying model

TK Hei, H Zhou, VN Ivanov, M Hong… - Journal of Pharmacy …, 2008 - academic.oup.com
The radiation-induced bystander effect represents a paradigm shift in our understanding of
the radiobiological effects of ionizing radiation, in that extranuclear and extracellular events …

Direct evidence for the participation of gap junction-mediated intercellular communication in the transmission of damage signals from α-particle irradiated to …

EI Azzam, SM De Toledo… - Proceedings of the …, 2001 - National Acad Sciences
It has generally been considered that important biological effects of ionizing radiation arise
as a direct consequence of DNA damage occurring in irradiated cells. We have examined …

Oxidative metabolism modulates signal transduction and micronucleus formation in bystander cells from α-particle-irradiated normal human fibroblast cultures

EI Azzam, SM De Toledo, DR Spitz, JB Little - Cancer research, 2002 - AACR
The role of oxidative metabolism in the up-regulation/activation of stress-induciblesignaling
pathways as well as induction of micronucleus formation in bystander cells was investigated …

Adaptive responses to low doses of radiation or chemicals: their cellular and molecular mechanisms

Y Guéguen, A Bontemps, TG Ebrahimian - Cellular and Molecular Life …, 2019 - Springer
This article reviews the current knowledge on the mechanisms of adaptive response to low
doses of ionizing radiation or chemical exposure. A better knowledge of these mechanisms …

Molecular mechanisms of low dose ionizing radiation-induced hormesis, adaptive responses, radioresistance, bystander effects, and genomic instability

FR Tang, WK Loke - International journal of radiation biology, 2015 - Taylor & Francis
Purposes: To review research progress on the molecular mechanisms of low dose ionizing
radiation (LDIR)-induced hormesis, adaptive responses, radioresistance, bystander effects …

Ion beam radiobiology and cancer: time to update ourselves

E Fokas, G Kraft, H An, R Engenhart-Cabillic - Biochimica et Biophysica …, 2009 - Elsevier
High-energy protons and carbon ions exhibit an inverse dose profile allowing for increased
energy deposition with penetration depth. Additionally, heavier ions like carbon beams have …

Advances in the current understanding of how low-dose radiation affects the cell cycle

MGM Khan, Y Wang - Cells, 2022 - mdpi.com
Cells exposed to ionizing radiation undergo a series of complex responses, including DNA
damage, reproductive cell death, and altered proliferation states, which are all linked to cell …

Intercellular and intracellular signaling pathways mediating ionizing radiation-induced bystander effects

N Hamada, H Matsumoto, T Hara… - Journal of radiation …, 2007 - academic.oup.com
A rapidly growing body of experimental evidence indicates that ionizing radiation induces
biological effects in non-irradiated bystander cells that have received signals from adjacent …

General aspects of the cellular response to low-and high-LET radiation

JP Pouget, SJ Mather - European journal of nuclear medicine, 2001 - Springer
Radiobiological studies have shown for some time that the effects of ionising radiation on
cells are mainly explained by modification of the DNA. Numerous studies over the past 50 …