In recent years, exceptional technological advances have enabled the identification and
interrogation of rare circulating tumour cells (CTCs) from blood samples of patients, leading …

Circulating tumor cell (CTC) clusters may represent one of the key mechanisms initiating the
metastasis process. However, the series of pathophysiologic events by which CTC clusters …

Gastric cancer (GC) is the most common gastrointestinal malignant tumor, and distant
metastasis is a critical factor in the prognosis of patients with GC. Understanding the …

The major cause of cancer-associated mortality is tumor metastasis, a disease that is far
from understood. Many studies have observed circulating tumor cells (CTCs) in patients' …

Neutrophils are the first responders to inflammation, infection, and injury. As one of the most
abundant leukocytes in the immune system, neutrophils play an essential role in cancer …

Collective metastasis is defined as the cohesive migration and metastasis of multicellular
tumor cell clusters. Disrupting various cell adhesion genes markedly reduces cluster …

To study how cancer cells can withstand fluid shear stress (SS), we isolated SS-resistant
breast and lung cancer cells using a microfluidic circulatory system. These SS-resistant cells …

Invasive breast cancer tends to metastasize to lymph nodes and systemic sites. The
management of metastasis has evolved by focusing on controlling the growth of the disease …

Circulating tumour cells (CTCs) are the metastatic precursors to distant disease in head and
neck cancers (HNCs). Whilst the prognostic and predictive value of single CTCs have been …

The metastatic process is arduous. Cancer cells must escape the confines of the primary
tumor, make their way into and travel through the circulation, then survive and proliferate in …