Depression is an episodic form of mental illness characterized by mood state transitions with
poorly understood neurobiological mechanisms. Antidepressants reverse the effects of …

Stress is associated with the onset and severity of several psychiatric disorders that occur
more frequently in women than men, including posttraumatic stress disorder (PTSD) and …

The Y-maze can be used to assess short term memory in mice. Spontaneous alternation, a
measure of spatial working memory, can be assessed by allowing mice to explore all three …

Dendritic spines are small protrusions studding neuronal dendrites, first described in 1888
by Ramón y Cajal using his famous Golgi stainings. Around 50 years later the advance of …

This review summarizes the brain mechanisms controlling sleep and wakefulness.
Wakefulness promoting systems cause low-voltage, fast activity in the …

Stress can affect cognition in many ways, with the outcome (ie, facilitating or impairing)
depending on a combination of factors related to both stress and the cognitive function …

The brain is the key organ of the response to stress because it determines what is
threatening and, therefore, potentially stressful, as well as the physiological and behavioral …

Following the discovery of glucocorticoid receptors in the hippocampus and other brain
regions, research has focused on understanding the effects of glucocorticoids in the brain …

Brain Corticosteroid Receptor Balance in Health and Disease* | Endocrine Reviews | Oxford
Academic Skip to Main Content Advertisement Oxford Academic Journals Books Search Menu …

The hormones and other physiological agents that mediate the effects of stress on the body
have protective and adaptive effects in the short run and yet can accelerate pathophysiology …