RNA-binding proteins in tumor progression

H Qin, H Ni, Y Liu, Y Yuan, T Xi, X Li… - Journal of hematology & …, 2020 - Springer
RNA-binding protein (RBP) has a highly dynamic spatiotemporal regulation process and
important biological functions. They are critical to maintain the transcriptome through post …

RNA-binding proteins and cancer metastasis

S Wang, Z Sun, Z Lei, HT Zhang - Seminars in cancer biology, 2022 - Elsevier
RNA-binding proteins (RBPs) can regulate gene expression through post-transcriptionally
influencing all manner of RNA biology, including alternative splicing (AS), polyadenylation …

Tumor temperature: friend or foe of virus-based cancer immunotherapy

JP Knapp, JE Kakish, BW Bridle, DJ Speicher - Biomedicines, 2022 - mdpi.com
The temperature of a solid tumor is often dissimilar to baseline body temperature and,
compared to healthy tissues, may be elevated, reduced, or a mix of both. The temperature of …

Molecular landscape of c-Myc signaling in prostate cancer: A roadmap to clinical translation

MA Faskhoudi, P Molaei, M Sadrkhanloo… - … -Research and Practice, 2022 - Elsevier
The c-Myc signaling is a new emerging target in cancer therapy. Activation of c-Myc
signaling leads to cancer growth and invasion in vitro and in vivo. The stability of c-Myc can …

The role of CSDE1 in translational reprogramming and human diseases

AX Guo, JJ Cui, LY Wang, JY Yin - Cell Communication and Signaling, 2020 - Springer
CSDE1 (cold shock domain containing E1) plays a key role in translational reprogramming,
which determines the fate of a number of RNAs during biological processes. Interestingly …

RNA-binding proteins regulate post-transcriptional responses to TGF-β to coordinate function and mesenchymal activation of murine endothelial cells

R Wardman, M Keles, I Pachkiv… - … and Vascular Biology, 2023 - Am Heart Assoc
BACKGROUND: Endothelial cells (ECs) are primed to respond to various signaling cues.
For example, TGF (transforming growth factor)-β has major effects on EC function and …

Mesenchymal stem cell-derived extracellular vesicles transmitting microRNA-34a-5p suppress tumorigenesis of colorectal cancer through c-MYC/DNMT3a/PTEN axis

J Zhao, H Lin, K Huang - Molecular neurobiology, 2022 - Springer
Mesenchymal stem cell–derived extracellular vesicles (MSC-EV) can transport microRNAs
(miRNAs) into colorectal cancer (CRC) cells, thus to inhibit the malignant phenotype of …

Significant position of C-myc in colorectal cancer: a promising therapeutic target

L Tan, D Peng, Y Cheng - Clinical and Translational Oncology, 2022 - Springer
Colorectal cancer (CRC) is a malignant tumor initiating from the mucosa of the colorectum.
According to the 2020 statistics from the World Health Organization, there are 10.0% CRC …

Post-transcriptional regulation of colorectal cancer: a focus on RNA-binding proteins

JM García-Cárdenas, S Guerrero… - Frontiers in molecular …, 2019 - frontiersin.org
Colorectal cancer (CRC) is a major health problem with an estimated 1. 8 million new cases
worldwide. To date, most CRC studies have focused on DNA-related aberrations, leaving …

Proteomics separates adult-type diffuse high-grade gliomas in metabolic subgroups independent of 1p/19q codeletion and across IDH mutational status

JM Bader, N Deigendesch, M Misch, M Mann… - Cell Reports …, 2023 - cell.com
High-grade adult-type diffuse gliomas are malignant neuroepithelial tumors with poor
survival rates in combined chemoradiotherapy. The current WHO classification is based on …