Tumors that express detectable levels of the product of the ESR1 gene (estrogen receptor-α;
ERα) represent the single largest molecular subtype of breast cancer. More women …

Growth factors mediate their diverse biologic responses (regulation of cellular proliferation,
differentiation, migration and survival) by binding to and activating cell-surface receptors …

Triple-negative breast cancer (TNBC) is a highly aggressive form of breast cancer that
exhibits extremely high levels of genetic complexity and yet a relatively uniform …

Chemotherapeutic and cytotoxic drugs are widely used in the treatment of cancer. In spite of
the improvements in the life quality of patients, their effectiveness is compromised by several …

The production of reactive oxygen and nitrogen species (ROS and RNS) in human cells is
implicated in various diseases, including cancer. Micrometer-sized electrodes coated with Pt …

PURPOSE To review the most important recent advances in clinical trials and biologic
studies within the growing field of chemoprevention. METHODS The most critical methods …

Breast cancer remains the leading cause of cancer death among females worldwide. It
signifies a shift from the previous decade during which the most common cause of cancer …

Increasing evidence suggests that HER2-amplified breast cancer cells use HER3/ErbB3 to
drive therapeutic resistance to HER2 inhibitors. However, the role of ErbB3 in the earliest …

We synthesized a new series of 2-[(3-(4-sulfamoylphenethyl)-4 (3H)-quinazolinon-2-yl) thio]
anilide derivatives (2–16) and evaluated their cytotoxic activity against breast …

Although it is widely accepted that better food habits do play important role in cancer
prevention and treatment, how dietary agents mediate their effects remains poorly …