Mechanisms involved in the relationship between vitamin D and insulin resistance: impact on clinical practice

V Contreras-Bolívar, B García-Fontana… - Nutrients, 2021 - mdpi.com
Recent evidence has revealed anti-inflammatory properties of vitamin D as well as extra-
skeletal activity. In this context, vitamin D seems to be involved in infections, autoimmune …

Role of vitamin D in the metabolic syndrome

L Melguizo-Rodríguez, VJ Costela-Ruiz… - Nutrients, 2021 - mdpi.com
The prevalence of hypovitaminosis D has risen in developed countries over the past few
years in association with lifestyle changes and an increase in unhealthy habits. Vitamin D …

[HTML][HTML] Adipose tissue: physiology to metabolic dysfunction

AJ Richard, U White, CM Elks, JM Stephens - Endotext [Internet], 2020 - ncbi.nlm.nih.gov
Like the obesity epidemic, our understanding of adipocytes and adipose tissue is
expanding. Just in the past decade, substantial advances have led to new insights into the …

Mineral oil: safety and use as placebo in REDUCE-IT and other clinical studies

B Olshansky, MK Chung, MJ Budoff… - European Heart …, 2020 - academic.oup.com
Mineral oil is often used as a clinical trial placebo. Pharmaceutical-grade mineral oil consists
of a mixture of saturated hydrocarbons, with a purity and chemical structure that differs …

The role of nutrition on meta-inflammation: insights and potential targets in communicable and chronic disease management

O Ramos-Lopez, D Martinez-Urbistondo… - Current Obesity …, 2022 - Springer
Abstract Purpose of Review Chronic low-grade inflammation may contribute to the onset and
progression of communicable and chronic diseases. This review examined the effects and …

Obesity and overweight decreases the effect of vitamin D supplementation in adults: systematic review and meta-analysis of randomized controlled trials

LF de Oliveira, LG de Azevedo… - Reviews in Endocrine …, 2020 - Springer
Overweight and obesity are associated with vitamin D deficiency (VitD), which are both
important health problems. Reduced serum vitamin D levels has been registered in all …

Adipose tissue aging and metabolic disorder, and the impact of nutritional interventions

X Wang, M Xu, Y Li - Nutrients, 2022 - mdpi.com
Adipose tissue is the largest and most active endocrine organ, involved in regulating energy
balance, glucose and lipid homeostasis and immune function. Adipose tissue aging …

Obesity-associated vitamin D deficiency correlates with adipose tissue DNA hypomethylation, inflammation, and vascular dysfunction

I Mirza, A Mohamed, H Deen, S Balaji… - International Journal of …, 2022 - mdpi.com
Vitamin D (VD) deficiency is a hallmark of obesity and vascular dysfunction. We sought to
test the hypothesis that VD deficiency may contribute to obesity-related vascular dysfunction …

Phase angle: A possible biomarker to quantify inflammation in subjects with obesity and 25 (OH) D deficiency

L Barrea, G Muscogiuri, D Laudisio, C Di Somma… - Nutrients, 2019 - mdpi.com
Obesity is associated to chronic low-grade metabolic inflammation and hypovitaminosis D.
Among extra-skeletal effects, an important role in inflammation has been described for …

Interrelationship between vitamin D and calcium in obesity and its comorbid conditions

IA Harahap, JF Landrier, J Suliburska - Nutrients, 2022 - mdpi.com
Obesity has been linked to vitamin D (VD) deficiency and low calcium (CAL) status. In the
last decade, dietary supplementation of vitamin D and calcium (VD–CAL) have been …