Conspectus Cyclometalated π-allyliridium-C, O-benzoate complexes discovered in the
Krische laboratory display unique amphiphilic properties, catalyzing both nucleophilic …

Recent years have witnessed the emergence of direct intermolecular C (sp3)–H bond
functionalization using in situ generated aryl/alkyl radicals as a unique class of hydrogen …

Asymmetric reactions that convert racemic mixtures into enantioenriched amines are of
significant importance due to the prevalence of amines in pharmaceuticals, with about 60 …

We describe the first total synthesis of the unusual cyclopropane-containing indole alkaloid
(−)-rauvomine B via a strategy centered upon intramolecular cyclopropanation of a …

Cobalt-bisoxazolinephosphine-catalyzed regio-and enantioselective allylic amination of
racemic n-propyl allylic carbonate and aniline was investigated by DFT calculations at the …

An efficient Ir-catalyzed asymmetric allylic amination reaction of alkyl-substituted allylic
carbonates is disclosed. With the Krische iridium complex as the catalyst, asymmetric allylic …

The mechanism of π-allyliridium C, O-benzoate-catalyzed allylic amination was studied by
(a) reaction progress kinetic analysis (RPKA),(b) tandem electrospray ionization–mass …

Forging quaternary stereocenters has long been sought after in the realm of modern
synthetic chemistry. Among the fundamental structural motifs in organic chemistry, the …

Enantioselective nucleophilic and electrophilic allylations mediated by racemic branched
allylic acetates and catalyzed by π-allyliridium C, O-benzoate complexes are described. The …