Peripheral tissue damage or nerve injury often leads to pathological pain processes, such as spontaneous pain, hyperalgesia and allodynia, that persist for years or decades after all …
“Fascinating. Doidge's book is a remarkable and hopeful portrait of the endless adaptability of the human brain.”—Oliver Sacks, MD, author of The Man Who Mistook His Wife for a Hat …
M Zimmermann - European journal of pharmacology, 2001 - Elsevier
This review deals with physiological and biological mechanisms of neuropathic pain, that is, pain induced by injury or disease of the nervous system. Animal models of neuropathic pain …
The classic definition of preemptive analgesia requires 2 groups of patients to receive identical treatment before or after incision or surgery. The only difference between the 2 …
L Nikolajsen, S Ilkjær, K Krøner, JH Christensen… - Pain, 1997 - Elsevier
The significance of preamputation pain for the development of postamputation stump and phantom pain has been discussed over the years and is still a matter of dispute. It has been …
RW Colburn, AJ Rickman, JA DeLeo - Experimental neurology, 1999 - Elsevier
A number of rat peripheral neuropathy models have been developed to simulate human neuropathic pain conditions. The current study sought to determine the relative importance …
R Melzack, TJ Coderre, J Katz… - Annals of the New York …, 2001 - Wiley Online Library
The traditional specificity theory of pain perception holds that pain involves a direct transmission system from somatic receptors to the brain. The amount of pain perceived …
Chronic pain is characterized by abnormal sensitivity, which is due to the generation of pain in response to the activation of the low-threshold mechanoreceptive AP fibres that normally …
Suffering is a state of mind that is difficult to measure and analyse in human beings and considerably more so in animals. It is related to the environment in which we live and our …