Fertility and infertility: Definition and epidemiology

M Vander Borght, C Wyns - Clinical biochemistry, 2018 - Elsevier
Infertility is a disease characterized by the failure to establish a clinical pregnancy after 12
months of regular and unprotected sexual intercourse. It is estimated to affect between 8 and …

Temporal trends in sperm count: a systematic review and meta-regression analysis

H Levine, N Jørgensen… - Human reproduction …, 2017 - academic.oup.com
BACKGROUND Reported declines in sperm counts remain controversial today and recent
trends are unknown. A definitive meta-analysis is critical given the predictive value of sperm …

Sperm DNA fragmentation testing: Summary evidence and clinical practice recommendations

SC Esteves, A Zini, RM Coward, DP Evenson… - Andrologia, 2021 - Wiley Online Library
We herein summarise the evidence concerning the impact of sperm DNA fragmentation in
various clinical infertility scenarios and the advances on sperm DNA fragmentation tests …

Reactive oxygen species and male reproductive hormones

M Darbandi, S Darbandi, A Agarwal… - Reproductive Biology …, 2018 - Springer
Reports of the increasing incidence of male infertility paired with decreasing semen quality
have triggered studies on the effects of lifestyle and environmental factors on the male …

Trends of male factor infertility, an important cause of infertility: A review of literature

N Kumar, AK Singh - Journal of human reproductive sciences, 2015 - journals.lww.com
Infertility and problems of impaired fecundity have been a concern through ages and is also
a significant clinical problem today, which affects 8–12% of couples worldwide. Of all …

Male reproductive disorders and fertility trends: influences of environment and genetic susceptibility

NE Skakkebaek, E Rajpert-De Meyts… - Physiological …, 2016 - journals.physiology.org
It is predicted that Japan and European Union will soon experience appreciable decreases
in their populations due to persistently low total fertility rates (TFR) below replacement level …

Human exposure to endocrine disrupting chemicals: effects on the male and female reproductive systems

S Sifakis, VP Androutsopoulos, AM Tsatsakis… - Environmental …, 2017 - Elsevier
Endocrine disrupting chemicals (EDCs) comprise a group of chemical compounds that have
been examined extensively due to the potential harmful effects in the health of human …

Spermatogenesis in humans and its affecting factors

FTL Neto, PV Bach, BB Najari, PS Li… - Seminars in cell & …, 2016 - Elsevier
Spermatogenesis is an extraordinary complex process. The differentiation of spermatogonia
into spermatozoa requires the participation of several cell types, hormones, paracrine …

[HTML][HTML] Obesity, male infertility, and the sperm epigenome

JR Craig, TG Jenkins, DT Carrell, JM Hotaling - Fertility and sterility, 2017 - Elsevier
Obesity is a growing epidemic and a common problem among reproductive-age men that
can both cause and exacerbate male-factor infertility by means of endocrine abnormalities …

Efficacy of psychosocial interventions for psychological and pregnancy outcomes in infertile women and men: a systematic review and meta-analysis

Y Frederiksen, I Farver-Vestergaard, NG Skovgård… - BMJ open, 2015 - bmjopen.bmj.com
Objective To evaluate the evidence on the efficacy of psychosocial interventions for
improving pregnancy rates and reducing distress for couples in treatment with assisted …