Neutrophils are major effectors and regulators of the immune system. They play critical roles
not only in the eradication of pathogens but also in cancer initiation and progression …

COVID-19 has quickly reached pandemic levels since it was first reported in December
2019. The virus responsible for the disease, named SARS-CoV-2, is enveloped positive …

Disclosures: MR Looney reported" other" from Neutrolis outside the submitted work. RE
Schwartz is a Sponsored Advisory Board Member for Miromatrix Inc. JD Spicer reported …

Clinical evidence indicates that the fatal outcome observed with severe acute respiratory
syndrome-coronavirus-2 infection often results from alveolar injury that impedes airway …

The transcription factor NF-κB is a central mediator of inflammation with multiple links to
thrombotic processes. In this review, we focus on the role of NF-κB signaling in cell types …

Disseminated intravascular coagulation (DIC) has been recognized as a deadly
complication in sepsis, and its early recognition followed by appropriate management of the …

Cancer-associated thrombosis is a major cause of mortality in cancer patients, the most
common type being venous thromboembolism (VTE). Several risk factors for developing …

The association between inflammation, infection, and venous thrombosis has long been
recognized; yet, only in the last decades have we begun to understand the mechanisms …

Neutrophils release neutrophil extracellular traps (NETs) which ensnare pathogens and
have pathogenic functions in diverse diseases. We examined the NETosis pathways …

Severe acute lung injury has few treatment options and a high mortality rate. Upon injury,
neutrophils infiltrate the lungs and form neutrophil extracellular traps (NETs), damaging the …