Any opinions, findings, and conclusions or recommendations expressed in this material are
those of the authors and do not necessarily reflect the views of the US Army Contracting …

Seizures are defined as a transient occurrence of signs and symptoms due to the abnormal,
excessive, or synchronous neuronal activity in the brain characterized by abrupt and …

Background Concerns exist regarding the impact of widely used clinical drugs on brain
development. This study investigates long-term neurocognitive functioning in relation to …

Objectives: To determine the feasibility of a personalized music intervention with
mechanically ventilated patients in the PICU. Design: Pilot study with a quasi-experimental …

The paediatric population is at risk of inadequate pain management, with age-related factors
affecting pain management in children. This presented study discusses the complexities of …

Background The gene ABCB1 encodes p-glycoprotein, a xenobiotic efflux pump capable of
transporting certain opioids, including fentanyl. ABCB1 genotype has been previously …

Background To evaluate the efficacy and safety of fentanyl for sedation therapy in
mechanically ventilated children. Methods This was a double-blind, randomized controlled …

Objectives To describe the use and outcomes of the neurological wake-up test (NWT) in
pediatric severe traumatic brain injury (pTBI). Design Retrospective single-center …

Objective To understand the use of tools, protocols and comfort measures related to
sedation/analgesia, and to screen the occurrence of delirium in pediatric intensive care …

Background Iatrogenic withdrawal syndrome is a well-known adverse effect of sedatives and
analgesics commonly used in patients receiving mechanical ventilation in the pediatric …