[HTML][HTML] Age-dependent genes in adipose stem and precursor cells affect regulation of fat cell differentiation and link aging to obesity via cellular and genetic …

A Kar, M Alvarez, KM Garske, H Huang, SHT Lee… - Genome medicine, 2024 - Springer
Background Age and obesity are dominant risk factors for several common cardiometabolic
disorders, and both are known to impair adipose tissue function. However, the underlying …

[HTML][HTML] Aligning cross-species interactomes for studying complex and chronic diseases

M Milano, P Cinaglia, PH Guzzi, M Cannataro - Life, 2023 - mdpi.com
Neurodegenerative diseases (NDs) are a group of complex disorders characterized by the
progressive degeneration and dysfunction of neurons in the central nervous system. NDs …

[HTML][HTML] Leveraging graph neural networks for supporting automatic triage of patients

A Defilippo, P Veltri, P Lió, PH Guzzi - Scientific Reports, 2024 - nature.com
Patient triage is crucial in emergency departments, ensuring timely and appropriate care
based on correctly evaluating the emergency grade of patient conditions. Triage methods …

Predicting Glycemia by Using RNNs and Heart Rate Patient Data

R Giancotti, P Vizza, M De Salazar… - … and Sensors (BATS), 2023 - ieeexplore.ieee.org
Type 1 diabetes mellitus (T1DM) is a chronic disease caused by the destruction of the
pancreatic beta cells resulting in an insufficient insulin production. This generates high …

Annotating omics Data with sex and age of samples: Enabling powerful omics studies

PH Guzzi, M Cannistra, R Giancotti… - 2023 IEEE …, 2023 - ieeexplore.ieee.org
There is increasing evidence that many molecular processes exhibit differences with age
and sex. Such differences produce also differences in the insurgence and progression of …

A novel Network Science Algorithm for Improving Triage of Patients

PH Guzzi, A Defilippo, P Veltri - 2023 IEEE International …, 2023 - ieeexplore.ieee.org
Patient triage plays a crucial role in healthcare, ensuring timely and appropriate care based
on the urgency of patient conditions. Traditional triage methods heavily rely on human …

Non Parametric Differential Network Analysis for Biological Data

PH Guzzi, A Roy, F Cortese, P Veltri - International Conference on …, 2023 - Springer
Rewiring of molecular interactions under different conditions causes different phenotypic
responses. Differential Network Analysis (also indicated as DNA) aims to investigate the …

Non Parametric Differential Network Analysis: A Tool for Unveiling Specific Molecular Signatures.

PH Guzzi, A Roy, M Milano, P Veltri - bioRxiv, 2024 - biorxiv.org
The rewiring of molecular interactions in various conditions leads to distinct phenotypic
outcomes. Differential Network Analysis (DNA) is dedicated to exploring these rewirings …

Focusing on Gender and Age Information as Lens for Gene Expression Data: Application to Dyslipidemia-based Atherosclerosis Data

PH Guzzi, E Pedace, P Veltri - 2023 - preprints.org
Dyslipidemia (Dys) is a disease characterised by abnormally high levels of lipids in the 1
blood. It causes the deposits of lipids on the arterial wall, leading to the insurgence of …

Bioinformatic Analysis of Sex and Age Factors of the Expression of the Genes Related to Dyslipidemia-based Atherosclerosis.

PH Guzzi, F Cortese, E Pedace, P Veltri - 2023 - preprints.org
Dyslipidemia (Dys) is a disease characterised by abnormally high levels of lipids in the
blood. It causes the deposits of lipids on the arterial wall leading to the insurgence of …