Cardiovascular diseases (CVDs) are the leading cause of death worldwide and represent a
major problem of public health. Over the years, life expectancy has considerably increased …

Matrikines originate from the fragmentation of extracellular matrix proteins and regulate
cellular activities by interacting with specific receptors. Matrikines are implicated in …

Biochemistry of Collagens, Laminins, and Elastin: Structure, Function and Biomarkers, Third
Edition provides current data on key structural proteins (collagens, laminins, and elastin) …

Elastic fibers are extracellular components of higher vertebrates and confer elasticity and
resilience to numerous tissues and organs such as large blood vessels, lungs, and skin …

Elastic fibers are an essential component of the extracellular matrix where they provide
structural integrity and elastic recoil in a number of important tissues. A major constituent of …

Vascular ageing, characterized by structural and functional changes in blood vessels of
which arterial stiffness and endothelial dysfunction are key components, is associated with …

Once considered as inert, the extracellular matrix recently revealed to be biologically active.
Elastin is one of the most important components of the extracellular matrix. Many vital organs …

Abdominal aortic aneurysm is a dynamic vascular disease characterized by inflammatory
cell invasion and extracellular matrix degradation. Damage to elastin in the extracellular …

Although it has long been established that the extracellular matrix acts as a mechanical
support, its degradation products, which mainly accumulate during aging, have also been …

The ubiquitous distribution of lysosomes and their heterogeneous protein composition
reflects the versatility of these organelles in maintaining cell homeostasis and their …