[HTML][HTML] SARS-CoV-2 viral load and shedding kinetics

O Puhach, B Meyer, I Eckerle - Nature Reviews Microbiology, 2023 - nature.com
SARS-CoV-2 viral load and detection of infectious virus in the respiratory tract are the two
key parameters for estimating infectiousness. As shedding of infectious virus is required for …

Lateral flow test engineering and lessons learned from COVID-19

J Budd, BS Miller, NE Weckman, D Cherkaoui… - Nature Reviews …, 2023 - nature.com
The acceptability and feasibility of large-scale testing with lateral flow tests (LFTs) for clinical
and public health purposes has been demonstrated during the COVID-19 pandemic. LFTs …

Onset and window of SARS-CoV-2 infectiousness and temporal correlation with symptom onset: a prospective, longitudinal, community cohort study

S Hakki, J Zhou, J Jonnerby… - The Lancet …, 2022 - thelancet.com
Background Knowledge of the window of SARS-CoV-2 infectiousness is crucial in
developing policies to curb transmission. Mathematical modelling based on scarce empirical …

Performance of rapid antigen tests for COVID-19 diagnosis: a systematic review and meta-analysis

MF Khalid, K Selvam, AJN Jeffry, MF Salmi, MA Najib… - Diagnostics, 2022 - mdpi.com
The identification of viral RNA using reverse transcription quantitative polymerase chain
reaction (RT-qPCR) is the gold standard for identifying an infection caused by SARS-CoV-2 …

Accuracy of rapid point-of-care antigen-based diagnostics for SARS-CoV-2: An updated systematic review and meta-analysis with meta-regression analyzing …

LE Brümmer, S Katzenschlager, S McGrath… - PLoS …, 2022 - journals.plos.org
Background Comprehensive information about the accuracy of antigen rapid diagnostic
tests (Ag-RDTs) for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is …

Immunocompromised patients with protracted COVID-19: a review of “long persisters”

V Dioverti, S Salto-Alejandre, G Haidar - Current transplantation reports, 2022 - Springer
Abstract Purpose of Review Certain immunocompromised individuals are at risk for
protracted COVID-19, in which SARS-CoV-2 leads to a chronic viral infection. However, the …

The P681H mutation in the spike glycoprotein of the alpha variant of SARS-CoV-2 escapes IFITM restriction and is necessary for type I interferon resistance

MJ Lista, H Winstone, HD Wilson, A Dyer… - Journal of …, 2022 - Am Soc Microbiol
The appearance of new dominant variants of concern (VOC) of severe acute respiratory
syndrome coronavirus type 2 (SARS-CoV-2) threatens the global response to the …

Efficacy of niclosamide vs placebo in SARS-CoV-2 respiratory viral clearance, viral shedding, and duration of symptoms among patients with mild to moderate COVID …

DM Cairns, D Dulko, JK Griffiths, Y Golan… - JAMA network …, 2022 - jamanetwork.com
Importance Oral anthelmintic niclosamide has potent in vitro antiviral activity against SARS-
CoV-2. Repurposed niclosamide could be a safe and efficacious COVID-19 therapy …

Performance of electrochemical immunoassays for clinical diagnostics of SARS-CoV-2 based on selective nucleocapsid N protein detection: Boron-doped diamond …

W Białobrzeska, M Ficek, B Dec, S Osella… - Biosensors and …, 2022 - Elsevier
The 21st century has already brought us a plethora of new threats related to viruses that
emerge in humans after zoonotic transmission or drastically change their geographic …

An updated review of SARS‐CoV‐2 detection methods in the context of a novel coronavirus pandemic

Y Zhang, Z Huang, J Zhu, C Li, Z Fang… - Bioengineering & …, 2023 - Wiley Online Library
Abstract The World Health Organization has reported approximately 430 million confirmed
cases of coronavirus disease 2019 (COVID‐19), caused by severe acute respiratory …