Migraine is a common, disabling neurological disorder characterized by multiple phases:
premonitory, aura, headache, postdrome, and interictal. Our understanding of the …

The central nervous system (CNS) is an immunologically specialized tissue protected by a
blood–brain barrier. The CNS parenchyma is enveloped by a series of overlapping …

Neurogenic inflammation, a well-defined pathophysiologial process is characterized by the
release of potent vasoactive neuropeptides, predominantly calcitonin gene-related peptide …

Ethnopharmacological relevance Migraines have become a major threat to human health,
as they significantly affect human health and quality of life due to a high prevalence rate …

Migraine is the most common neurological disorder in the world, affecting 12% of the
population. Migraine involves the central nervous system, trigeminal nerves and meninges …

Brain is a central and pivotal organ of human body containing the highest lipids content next
to adipose tissue. It works as a monitor for the whole body and needs an adequate supply of …

Background Migraine is a complex, multifaceted, and disabling headache disease that is
often complicated by gastrointestinal (GI) conditions, such as gastroparesis, functional …

Migraine is a primary headache disorder which has complex neurogenic pathophysiological
mechanisms still requiring full elucidation. The sensory nerves and meningeal mast cell …

There is evidence of the therapeutic potential of intranasal oxytocin for the treatment of pain
and various psychiatric disorders, however, there is scant evidence that oxytocin reaches …

Background: Migraine is a disabling neuroinflammatory condition characterized by
increasing the levels of interleukin (IL)-6, a proinflammatory cytokine and C-reactive protein …