suPAR: the molecular crystal ball

M Thunø, B Macho, J Eugen-Olsen - Disease markers, 2009 - Wiley Online Library
soluble urokinase Plasminogen Activator Receptor (suPAR) levels reflect inflammation and
elevated suPAR levels are found in several infectious diseases and cancer. suPAR exists in …

Myofibroblasts and the extracellular matrix network in post-myocardial infarction cardiac remodeling

Y Ma, LE de Castro Brás, H Toba, RP Iyer… - … -European Journal of …, 2014 - Springer
The cardiac extracellular matrix (ECM) fills the space between cells, supports tissue
organization, and transduces mechanical, chemical, and biological signals to regulate …

[HTML][HTML] Correlation of serum levels of vitronectin, malondialdehyde and Hs-CRP with disease severity in coronary artery disease

A Yaghoubi, M Ghojazadeh, S Abolhasani… - … of cardiovascular and …, 2015 - ncbi.nlm.nih.gov
Abstract Introduction: Vitronectin (VN), malondialdehyde (MDA) and high-sensitivity C-
reactive rotein (hs-CRP) are cooperative agents involved in the atherosclerosis process. The …

Cell-derived biomimetic nanoparticles as a novel drug delivery system for atherosclerosis: predecessors and perspectives

L Yang, G Zang, J Li, X Li, Y Li… - Regenerative …, 2020 - academic.oup.com
Atherosclerosis is a key mechanism underlying the pathogenesis of cardiovascular disease,
which is associated with high morbidity and mortality. In the field of precision medicine for …

Are low inflammatory reactions involved in exudative age-related macular degeneration? Morphological and immunhistochemical analysis of AMD associated with …

A Lommatzsch, P Hermans, KD Müller… - Graefe's Archive for …, 2008 - Springer
Purpose Basal laminar and linear deposits (BLD) are associated with the development of
choroidal neovascularization (CNV). Therefore, analysis of BLD composition may provide …

Development potential of extracellular matrix hydrogels as hemostatic materials

D Cai, W Weng - Frontiers in Bioengineering and Biotechnology, 2023 - frontiersin.org
The entry of subcutaneous extracellular matrix proteins into the circulation is a key step in
hemostasis initiation after vascular injury. However, in cases of severe trauma, extracellular …

Formation of soluble amyloid oligomers and amyloid fibrils by the multifunctional protein vitronectin

TM Shin, JM Isas, CL Hsieh, R Kayed… - Molecular …, 2008 - Springer
Background The multifunctional protein vitronectin is present within the deposits associated
with Alzheimer disease (AD), age-related macular degeneration (AMD), atherosclerosis …

Functional connections and pathways of coenzyme Q10‐inducible genes: An in‐silico study

F Döring, C Schmelzer, I Lindner, C Vock, K Fujii - IUBMB life, 2007 - Wiley Online Library
Abstract Coenzyme Q10 (CoQ10, ubiquinone) is an essential cofactor in the electron
transport chain, serves as a potent antioxidant in mitochondria and lipid membranes, and is …

Solid-state NMR MAS CryoProbe enables structural studies of human blood protein vitronectin bound to hydroxyapatite

T Gopinath, K Shin, Y Tian, W Im, J Struppe… - Journal of Structural …, 2024 - Elsevier
The low sensitivity of nuclear magnetic resonance (NMR) is a major bottleneck for studying
biomolecular structures of complex biomolecular assemblies. Cryogenically cooled probe …

Discovery of proteins related to coronary artery disease using industrial-scale proteomics analysis of pooled plasma

MP Donahue, K Rose, D Hochstrasser… - American heart …, 2006 - Elsevier
BACKGROUND: Relating a disease state to an entire population of proteins provides an
opportunity to gain new insights into a disease. METHODS: Male populations of 53 patients …