In vitro models are essential to a broad range of biomedical research, such as pathological
studies, drug development, and personalized medicine. As a potentially transformative …

Many different epithelial and endothelial barriers in the human body ensure the proper
functioning of our organs by controlling which substances can pass from one side to …

Neurodegenerative diseases (NDDs) affect more than 50 million people worldwide, posing
a significant global health challenge as well as a high socioeconomic burden. With aging …

A hydroxycinnamic acid derivative, namely ferulic acid (FA) has been successfully
encapsulated in polymeric nanoparticles (NPs) based on poly (lactic-co-glycolic …

Neurovascular unit (NVU) inflammation via activation of glial cells and neuronal damage
plays a critical role in neurodegenerative diseases. Though the exact mechanism of disease …

The blood–brain barrier (BBB) is a fundamental structure that protects the composition of the
brain by determining which ions, metabolites, and nutrients are allowed to enter the brain …

The blood–brain barrier, which is formed by tightly interconnected microvascular endothelial
cells, separates the brain from the peripheral circulation. Together with other central nervous …

Bioassembly encompasses various techniques such as bioprinting, microfluidics, organoids,
and self-assembly, enabling advances in tissue engineering and regenerative medicine …

Many neurodegenerative diseases are identified but their causes and cure are far from
being well-known. The problem resides in the complexity of the neural tissue and its location …

A great progress has been made in the development and use of lab-on-a-chip devices to
model and study the blood–brain barrier (BBB) in the last decade. We present the main …