[HTML][HTML] Understanding the dynamics of physiological changes, protein expression, and PFAS in wildlife
Per-and polyfluoroalkyl substances (PFAS) accumulation and elimination in both wildlife
and humans is largely attributed to PFAS interactions with proteins, including but not limited …
and humans is largely attributed to PFAS interactions with proteins, including but not limited …
Emergence of SARS-CoV-2 through recombination and strong purifying selection
COVID-19 has become a global pandemic caused by the novel coronavirus SARS-CoV-2.
Understanding the origins of SARS-CoV-2 is critical for deterring future zoonosis …
Understanding the origins of SARS-CoV-2 is critical for deterring future zoonosis …
Continuous evolution of base editors with expanded target compatibility and improved activity
BW Thuronyi, LW Koblan, JM Levy, WH Yeh… - Nature …, 2019 - nature.com
Base editors use DNA-modifying enzymes targeted with a catalytically impaired CRISPR
protein to precisely install point mutations. Here, we develop phage-assisted continuous …
protein to precisely install point mutations. Here, we develop phage-assisted continuous …
Phase-plate cryo-EM structure of a class B GPCR–G-protein complex
Class B G-protein-coupled receptors are major targets for the treatment of chronic diseases,
such as osteoporosis, diabetes and obesity. Here we report the structure of a full-length …
such as osteoporosis, diabetes and obesity. Here we report the structure of a full-length …
TMC1 forms the pore of mechanosensory transduction channels in vertebrate inner ear hair cells
B Pan, N Akyuz, XP Liu, Y Asai, C Nist-Lund, K Kurima… - Neuron, 2018 - cell.com
The proteins that form the permeation pathway of mechanosensory transduction channels in
inner-ear hair cells have not been definitively identified. Genetic, anatomical, and …
inner-ear hair cells have not been definitively identified. Genetic, anatomical, and …
The Treponema pallidum Outer Membrane
The outer membrane (OM) of Treponema pallidum, the uncultivatable agent of venereal
syphilis, has long been the subject of misconceptions and controversy. Decades ago …
syphilis, has long been the subject of misconceptions and controversy. Decades ago …
Structure of nonstructural protein 1 from SARS-CoV-2
The periodic emergence of novel coronaviruses (CoVs) represents an ongoing public health
concern with significant health and financial burdens worldwide. The most recent …
concern with significant health and financial burdens worldwide. The most recent …
Prophage-mediated defence against viral attack and viral counter-defence
RM Dedrick, D Jacobs-Sera, CAG Bustamante… - Nature …, 2017 - nature.com
Temperate phages are common, and prophages are abundant residents of sequenced
bacterial genomes. Mycobacteriophages are viruses that infect mycobacterial hosts …
bacterial genomes. Mycobacteriophages are viruses that infect mycobacterial hosts …
[HTML][HTML] Protein structure analysis of the interactions between SARS-CoV-2 spike protein and the human ACE2 receptor: from conformational changes to novel …
I Mercurio, V Tragni, F Busto, A De Grassi… - Cellular and Molecular …, 2021 - Springer
The recent severe acute respiratory syndrome, known as Coronavirus Disease 2019
(COVID-19) has spread so much rapidly and severely to induce World Health Organization …
(COVID-19) has spread so much rapidly and severely to induce World Health Organization …
Antimicrobial peptides grafted onto the surface of N-acetylcysteine-chitosan nanoparticles can revitalize drugs against clinical isolates of Mycobacterium tuberculosis
Tuberculosis is caused by Mycobacterium tuberculosis (MTB) and is the leading cause of
death from infectious diseases in the World. The search for new antituberculosis drugs is a …
death from infectious diseases in the World. The search for new antituberculosis drugs is a …