A decade ago, we hypothesized that drug addiction can be viewed as a transition from
voluntary, recreational drug use to compulsive drug-seeking habits, neurally underpinned by …

Brain imaging technology has allowed researchers to conduct rigorous studies of the
dynamic course of alcoholism through periods of drinking, sobriety, and relapse and to gain …

Objective: To review deficits in emotional processing and social cognition potentially
contributing to the dysfunctional emotion regulation and difficulties with interpersonal …

We review drug addiction from the perspective of the hypothesis that drugs of abuse interact
with distinct brain memory systems. We focus on emotional and procedural forms of memory …

Although gray matter (GM) damages caused by long term and excessive alcohol
consumption have long been reported, the structural neuroimaging findings on alcohol-use …

Alcohol use and misuse is increasing among women. Although the prevalence of drinking
remains higher in men than women, the gender gap is narrowing. This narrative review …

Substance use disorders (SUDs) are characterized by a compulsion to seek and consume
one or more substances of abuse, with a perceived loss of control and a negative emotional …

Background Many studies have revealed a widespread pattern of gray matter (GM) atrophy
by using voxel-based morphometry (VBM) studies involving the pathophysiology of alcohol …

Delineating common and separable neural alterations in substance use disorders (SUD) is
imperative to understand the neurobiological basis of the addictive process and to inform …

Alcohol use typically is initiated during adolescence, a period that coincides with critical
structural and functional maturation of the brain. Brain maturation and associated …