The vast majority of lungs used in clinical transplantation are donated after brain death
(DBD). The utilization of DBD lungs is low due to brain death-induced lung injury. Moreover …

Background Prognostic factors in lung transplantation are those variables that are
associated with transplant outcomes. Knowledge of donor and recipient prognostic variables …

The first 2 living recipients of pig hearts died unexpectedly within 2 months, despite both
recipients receiving what over 30 years of nonhuman primate (NHP) research would …

A brain-death-induced cytokine storm damages organs in an organ donor. However, a
longer time period between declaration of brain death and organ procurement (procurement …

Brain death-induced cytokine storm is thought to harm transplantable organs. However,
longer procurement times have been associated with non-inferior or better outcomes in …

Results In total, 2388 and 101,474 kidney transplantations in Finland and the United States
were included, respectively. The median procurement delay was 9.8 hours (interquartile …

Because donor authorization is not consent, family consent would not be required for
procedures performed on a brain-dead patient. Theoretically, the direction of a patient's care …

Acute kidney injury (AKI) and primary graft dysfunction (PGD) are serious complications after
heart transplantation (HT). The relationship between AKI and PGD is poorly understood. We …

Introduction Brain death (BD) compromises the viability of the lung for donation. Hypertonic
saline solution (HSS) induces rapid intravascular volume expansion and immunomodulatory …

New studies have questioned previous considerations of donor eligibility, demonstrating the
ability to use donated organs from a wider pool of possible donors, with less exclusion for …