Over the past decade, mass spectrometry (MS)-based “shotgun lipidomics” has emerged as
a powerful tool for quantitative and qualitative analysis of the complex lipids in the biological …

In the present study, we discuss the recent developments in oxysterol research. Exciting
results have been reported relating to the involvement of oxysterols in the fields of …

Background Therapies targeting estrogenic stimulation in estrogen receptor-positive (ER+)
breast cancer (BC) reduce mortality, but resistance remains a major clinical problem …

Nano-liquid chromatography (nLC)–nanoelectrospray (NSI) is one of the cornerstones of
mass-spectrometry-based bioanalytics. Nevertheless, the application of nLC is not yet …

The neuropeptide oxytocin (OT) is associated with a plethora of social behaviors and is a
key topic at the intersection of psychology and biology. However, tools for measuring OT are …

The inclusion of preliminary chemical labeling (derivatization) in the analysis process by
such powerful and widespread methods as electrospray ionization (ESI) and matrix-assisted …

BACKGROUND Global sterol analysis is challenging owing to the extreme diversity of sterol
natural products, the tendency of cholesterol to dominate in abundance over all other …

Dysregulated cholesterol metabolism is implicated in a number of neurological disorders.
Many sterols, including cholesterol and its precursors and metabolites, are biologically …

Liquid chromatography coupled to mass spectrometry (LC-MS) is one of the most powerful
tools in identifying and quantitating molecular species. Decreasing column diameter from …

Plant sterols (PS) are cholesterol-like terpenoids widely spread in the kingdom Plantae.
Being the target of extensive research for more than a century, PS have topped with …