Graft-versus-host disease prophylaxis: Pathophysiology-based review on current approaches and future directions
N Martinez-Cibrian, R Zeiser, JA Perez-Simon - Blood reviews, 2021 - Elsevier
Graft-versus-host disease (GvHD) was first described in 1959, since then major efforts have
been made in order to understand its physiopathology and animal models have played a …
been made in order to understand its physiopathology and animal models have played a …
[HTML][HTML] Mechanisms of graft-versus-host disease prevention by post-transplantation cyclophosphamide: an evolving understanding
NS Nunes, CG Kanakry - Frontiers in immunology, 2019 - frontiersin.org
Post-transplantation cyclophosphamide (PTCy) has been highly successful at preventing
severe acute and chronic graft-versus-host disease (GVHD) after allogeneic hematopoietic …
severe acute and chronic graft-versus-host disease (GVHD) after allogeneic hematopoietic …
Diagnosis and management of AML in adults: 2022 recommendations from an international expert panel on behalf of the ELN
The 2010 and 2017 editions of the European LeukemiaNet (ELN) recommendations for
diagnosis and management of acute myeloid leukemia (AML) in adults are widely …
diagnosis and management of acute myeloid leukemia (AML) in adults are widely …
Donor clonal hematopoiesis and recipient outcomes after transplantation
CJ Gibson, HT Kim, L Zhao, HM Murdock… - Journal of Clinical …, 2022 - ascopubs.org
PURPOSE Clonal hematopoiesis (CH) can be transmitted from a donor to a recipient during
allogeneic hematopoietic cell transplantation. Exclusion of candidate donors with CH is …
allogeneic hematopoietic cell transplantation. Exclusion of candidate donors with CH is …
[HTML][HTML] Posttransplantation cyclophosphamide prevents graft-versus-host disease by inducing alloreactive T cell dysfunction and suppression
LP Wachsmuth, MT Patterson… - The Journal of …, 2019 - Am Soc Clin Investig
Posttransplantation cyclophosphamide (PTCy) recently has had a marked impact on human
allogeneic hematopoietic cell transplantation (HCT). Yet our understanding of how PTCy …
allogeneic hematopoietic cell transplantation (HCT). Yet our understanding of how PTCy …
Impact of diagnostic genetics on remission MRD and transplantation outcomes in older patients with AML
HM Murdock, HT Kim, N Denlinger… - Blood, The Journal …, 2022 - ashpublications.org
Older patients with acute myeloid leukemia (AML) have high relapse risk and poor survival
after allogeneic hematopoietic cell transplantation (HCT). Younger patients may receive …
after allogeneic hematopoietic cell transplantation (HCT). Younger patients may receive …
Reduced-intensity transplantation for lymphomas using haploidentical related donors versus HLA-matched sibling donors: a Center for International Blood and …
Purpose Related donor haploidentical hematopoietic cell transplantation (Haplo-HCT) using
post-transplantation cyclophosphamide (PT-Cy) is increasingly used in patients lacking HLA …
post-transplantation cyclophosphamide (PT-Cy) is increasingly used in patients lacking HLA …
Haploidentical BMT for severe aplastic anemia with intensive GVHD prophylaxis including posttransplant cyclophosphamide
Severe aplastic anemia (SAA) is a stem cell disorder often treated with bone marrow
transplantation (BMT) to reconstitute hematopoiesis. Outcomes of related HLA …
transplantation (BMT) to reconstitute hematopoiesis. Outcomes of related HLA …
Bone marrow versus mobilized peripheral blood stem cells in haploidentical transplants using posttransplantation cyclophosphamide
BACKGROUND Incidence of graft‐versus‐host disease (GVHD) in haploidentical bone
marrow (BM) transplants using posttransplantion cyclophosphamide (PT‐Cy) is low …
marrow (BM) transplants using posttransplantion cyclophosphamide (PT‐Cy) is low …
Reduced post-transplant cyclophosphamide doses in haploidentical hematopoietic cell transplantation for elderly patients with hematological malignancies
Although post-transplant cyclophosphamide (PT-Cy) is effective for graft-versus-host
disease (GVHD) prophylaxis, it is associated with toxicities, which might be dose-dependent …
disease (GVHD) prophylaxis, it is associated with toxicities, which might be dose-dependent …