Broadly neutralizing antibodies to SARS-CoV-2 and other human coronaviruses

Y Chen, X Zhao, H Zhou, H Zhu, S Jiang… - Nature Reviews …, 2023 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a recently emerged
pathogenic human coronavirus that belongs to the sarbecovirus lineage of the genus …

Exploring dendrimer-based drug delivery systems and their potential applications in cancer immunotherapy

S Mukherjee, S Mukherjee, MAS Abourehab… - European Polymer …, 2022 - Elsevier
Cancer immunotherapy has been researched as a major modality of treatment which
involves activating the immune system of the patient to fight against tumor cells. Dendrimers …

Modular-designed engineered bacteria for precision tumor immunotherapy via spatiotemporal manipulation by magnetic field

X Ma, X Liang, Y Li, Q Feng, K Cheng, N Ma… - Nature …, 2023 - nature.com
Micro-nano biorobots based on bacteria have demonstrated great potential for tumor
diagnosis and treatment. The bacterial gene expression and drug release should be …

Nanoparticle‐based bioaffinity assays: from the research laboratory to the market

Z Farka, JC Brandmeier, MJ Mickert… - Advanced …, 2024 - Wiley Online Library
Advances in the development of new biorecognition elements, nanoparticle‐based labels as
well as instrumentation have inspired the design of new bioaffinity assays. This review …

TROP2-directed nanobody-drug conjugate elicited potent antitumor effect in pancreatic cancer

C Xu, M Zhu, Q Wang, J Cui, Y Huang, X Huang… - Journal of …, 2023 - Springer
Background Pancreatic cancer is a highly aggressive malignancy with limited treatment
options and a poor prognosis. Trophoblast cell surface antigen 2 (TROP2), a cell surface …

Nanocarriers: a reliable tool for the delivery of anticancer drugs

H Sabit, M Abdel-Hakeem, T Shoala, S Abdel-Ghany… - Pharmaceutics, 2022 - mdpi.com
Nanomedicines have gained popularity due to their potential therapeutic applications,
especially cancer treatment. Targeted nanoparticles can deliver drugs directly to cancer …

A Golgi‐Targeted Platinum Complex Plays a Dual Role in Autophagy Regulation for Highly Efficient Cancer Therapy

BB Liang, Q Liu, B Liu, HG Yao, J He… - Angewandte …, 2023 - Wiley Online Library
Regulating autophagy to control the homeostatic recycling process of cancer cells is a
promising anticancer strategy. Golgi apparatus is a substrate of autophagy but the Golgi …

GPC3-targeted immunoPET imaging of hepatocellular carcinomas

S An, D Zhang, Y Zhang, C Wang, L Shi, W Wei… - European journal of …, 2022 - Springer
Purpose Early detection of hepatocellular carcinoma (HCC) remains a clinical challenge.
Glypican 3 (GPC3) is a proteoglycan highly specific for HCC and is a potential diagnostic …

Nanobodies: from structure to applications in non-injectable and bispecific biotherapeutic development

B Li, X Qin, LZ Mi - Nanoscale, 2022 - pubs.rsc.org
The increasing demand for convenient, miniaturized and multifunctional antibodies
necessitates the development of novel antigen-recognition molecules for biological and …

Immuno-PET of colorectal cancer with a CEA-targeted [68 Ga] Ga-nanobody: From bench to bedside

L Li, X Lin, L Wang, X Ma, Z Zeng, F Liu, B Jia… - European Journal of …, 2023 - Springer
Purpose An accurate diagnosis of colorectal carcinoma (CRC) can assist physicians in
developing reasonable therapeutic regimens, thereby significantly improving the patient's …