Despite two decades of intensified research to understand and cure tuberculosis disease,
biological uncertainties remain and hamper progress. However, owing to collaborative …

Drug resistant tuberculosis contributes significantly to the global burden of antimicrobial
resistance, often consuming a large proportion of the healthcare budget and associated …

Bacteria possess an extraordinary repertoire of cell envelope glycans that have critical
physiological functions. Pathogenic bacteria have glycans that are essential for growth and …

BACKGROUND: Tuberculosis (TB) preventive therapy (TPT) decreases the risk of
developing TB disease and its associated morbidity and mortality. The aim of these clinical …

Interrupting transmission events is critical to tuberculosis control. Cough-generated aerosol
cultures predict tuberculosis transmission better than microbiological or clinical markers. We …

Coronavirus disease (Covid-19) has not only shaped awareness of the impact of infectious
diseases on global health. It has also provided instructive lessons for better prevention …

Tuberculosis has affected humankind for thousands of years, but a deeper understanding of
its cause and transmission only arose after Robert Koch discovered Mycobacterium …

Rationale: Interrupting tuberculosis (TB) transmission requires an improved understanding
of how and when the causative organism, Mycobacterium tuberculosis (Mtb), is aerosolized …

Conspectus The spread of infectious diseases due to travel and trade can be seen
throughout history, whether from early settlers or traveling businessmen. Increased …

Potential Mycobacterium tuberculosis (Mtb) transmission during different pulmonary
tuberculosis (TB) disease states is poorly understood. We quantified viable aerosolized Mtb …