Abstract Carnosine (β-alanyl-l-histidine) was discovered in 1900 as an abundant non-
protein nitrogen-containing compound of meat. The dipeptide is not only found in skeletal …

Calcium signaling underlies much of physiology. Almost all the Ca2+ in the cytoplasm is
bound to buffers, with typically only∼ 1% being freely ionized at resting levels in most cells …

Carnosine is a dipeptide synthesized in the body from β-alanine and L-histidine. It is found
in high concentrations in the brain, muscle, and gastrointestinal tissues of humans and is …

Carnosine (β-alanyl-l-histidine) and homocarnosine (γ-aminobutyric acid-l-histidine) are two
naturally occurring dipeptides with potential neuroprotective and neurotransmitter functions …

First isolated and characterized in 1900 by Gulewitsch, carnosine (β-alanyl-L-hystidine) is a
dipeptide commonly present in mammalian tissue, and in particular in skeletal muscle cells; …

The advanced glycation end-product (AGE) hypothesis proposes that accelerated chemical
modification of proteins by glucose during hyperglycemia contributes to the pathogenesis of …

The dipeptide carnosine has been observed to exert antiaging activity at cellular and whole
animal levels. This review discusses the possible mechanisms by which carnosine may …

L-Carnosine, a dipeptide, can enhance frontal lobe function or be neuroprotective. It can
also correlate with γ-aminobutyric acid (GABA)-homocarnosine interaction, with possible …

Occupational exposures to inhalation of certain metal dusts or aerosols can cause loss of
olfactory acuity, atrophy of the nasal mucosa, mucosal ulcers, perforated nasal septum, or …

Background The pathogenic road map leading to Alzheimer's disease (AD) is still not
completely understood; however, a large body of studies in the last few years supports the …