Neuronal circuitry for pain processing in the dorsal horn

AJ Todd - Nature Reviews Neuroscience, 2010 - nature.com
Neurons in the spinal dorsal horn process sensory information, which is then transmitted to
several brain regions, including those responsible for pain perception. The dorsal horn …

Glutamate uptake

NC Danbolt - Progress in neurobiology, 2001 - Elsevier
Brain tissue has a remarkable ability to accumulate glutamate. This ability is due to
glutamate transporter proteins present in the plasma membranes of both glial cells and …

Dorsal horn parvalbumin neurons are gate-keepers of touch-evoked pain after nerve injury

H Petitjean, SA Pawlowski, SL Fraine, B Sharif… - Cell reports, 2015 - cell.com
Neuropathic pain is a chronic debilitating disease that results from nerve damage, persists
long after the injury has subsided, and is characterized by spontaneous pain and …

Identifying functional populations among the interneurons in laminae I-III of the spinal dorsal horn

AJ Todd - Molecular pain, 2017 - journals.sagepub.com
The spinal dorsal horn receives input from primary afferent axons, which terminate in a
modality-specific fashion in different laminae. The incoming somatosensory information is …

Spinal circuits for touch, pain, and itch

SC Koch, D Acton, M Goulding - Annual review of physiology, 2018 - annualreviews.org
The exteroceptive somatosensory system is important for reflexive and adaptive behaviors
and for the dynamic control of movement in response to external stimuli. This review outlines …

[图书][B] Sensory mechanisms of the spinal cord: Volume 1 primary afferent neurons and the spinal dorsal horn

WD Willis Jr, RE Coggeshall - 2012 - books.google.com
The third edition of this monograph continues to have the goal of providing an overview of
current thought about the spinal cord mechanisms that are responsible for sensory …

Lbx1 specifies somatosensory association interneurons in the dorsal spinal cord

MK Gross, M Dottori, M Goulding - Neuron, 2002 - cell.com
Association and relay neurons that are generated in the dorsal spinal cord play essential
roles in transducing somatosensory information. During development, these two major …

Central nervous system targets: inhibitory interneurons in the spinal cord

DI Hughes, AJ Todd - Neurotherapeutics, 2020 - Springer
Pain is a percept of critical importance to our daily survival. In most cases, it serves both an
adaptive function by helping us respond appropriately in a potentially hostile environment …

[图书][B] The mouse nervous system

C Watson, G Paxinos, L Puelles - 2011 - books.google.com
The Mouse Nervous System provides a comprehensive account of the central nervous
system of the mouse. The book is aimed at molecular biologists who need a book that …

Increased abundance of opioid receptor heteromers after chronic morphine administration

A Gupta, J Mulder, I Gomes, R Rozenfeld, I Bushlin… - Science …, 2010 - science.org
The μ and δ types of opioid receptors form heteromers that exhibit pharmacological and
functional properties distinct from those of homomeric receptors. To characterize these …