The molecular mechanisms and therapeutic strategies of EMT in tumor progression and metastasis
Y Huang, W Hong, X Wei - Journal of hematology & oncology, 2022 - Springer
Epithelial–mesenchymal transition (EMT) is an essential process in normal embryonic
development and tissue regeneration. However, aberrant reactivation of EMT is associated …
development and tissue regeneration. However, aberrant reactivation of EMT is associated …
Context-dependent EMT programs in cancer metastasis
Epithelial–mesenchymal transition (EMT) is a developmental process whereby stationary,
adherent cells acquire the ability to migrate. EMT is critical for dramatic cellular movements …
adherent cells acquire the ability to migrate. EMT is critical for dramatic cellular movements …
Cytoplasmic functions of long noncoding RNAs
Long noncoding RNAs (lncRNAs) are transcripts longer than 200 nucleotides found
throughout the cell that lack protein‐coding function. Their functions are closely linked to …
throughout the cell that lack protein‐coding function. Their functions are closely linked to …
The rise of regulatory RNA
KV Morris, JS Mattick - Nature Reviews Genetics, 2014 - nature.com
Discoveries over the past decade portend a paradigm shift in molecular biology. Evidence
suggests that RNA is not only functional as a messenger between DNA and protein but also …
suggests that RNA is not only functional as a messenger between DNA and protein but also …
Revealing protein–lncRNA interaction
F Ferre, A Colantoni… - Briefings in …, 2016 - academic.oup.com
Long non-coding RNAs (lncRNAs) are associated to a plethora of cellular functions, most of
which require the interaction with one or more RNA-binding proteins (RBPs); similarly, RBPs …
which require the interaction with one or more RNA-binding proteins (RBPs); similarly, RBPs …
[HTML][HTML] Long noncoding RNA GMAN, up-regulated in gastric cancer tissues, is associated with metastasis in patients and promotes translation of ephrin A1 by …
Background & Aims We aimed to identify long noncoding RNAs (lncRNAs) that are up-
regulated in gastric cancer tissues from patients and study their function in gastric tumor …
regulated in gastric cancer tissues from patients and study their function in gastric tumor …
LncRNA GABPB1-AS1 and GABPB1 regulate oxidative stress during erastin-induced ferroptosis in HepG2 hepatocellular carcinoma cells
W Qi, Z Li, L Xia, J Dai, Q Zhang, C Wu, S Xu - Scientific reports, 2019 - nature.com
Ferroptosis is a non-apoptotic, iron-dependent oxidative form of cell death that is specifically
induced by erastin in RAS mutant cancer cells. Ferroptotic cell death is the result of …
induced by erastin in RAS mutant cancer cells. Ferroptotic cell death is the result of …
The functional role of long non-coding RNAs and epigenetics
J Cao - Biological procedures online, 2014 - Springer
Long non-coding RNAs (lncRNAs) are non-protein coding transcripts longer than 200
nucleotides. The post-transcriptional regulation is influenced by these lncRNAs by …
nucleotides. The post-transcriptional regulation is influenced by these lncRNAs by …
HIF2-induced long noncoding RNA RAB11B-AS1 promotes hypoxia-mediated angiogenesis and breast cancer metastasis
Hypoxia induces a vast array of long noncoding RNAs (lncRNA) in breast cancer cells, but
their biological functions remain largely unknown. Here, we identified a hitherto …
their biological functions remain largely unknown. Here, we identified a hitherto …
[HTML][HTML] Epigenetic mechanisms and the hallmarks of cancer: An intimate affair
N Darwiche - American journal of cancer research, 2020 - ncbi.nlm.nih.gov
Epigenetic mechanisms comprising DNA methylation, histone modifications, and noncoding
RNAs affect chromatin structure and regulate gene expression. These mechanisms control …
RNAs affect chromatin structure and regulate gene expression. These mechanisms control …