Alzheimer's disease is a chronic and progressive brain neurodegenerative disease affecting
over 30 million people globally. Currently, no effective treatment is available due to multiple …

Alzheimer's disease (AD) is considered the sixth leading cause of death in elderly patients
and is characterized by progressive neuronal degeneration and impairment in memory …

Antibacterial resistance poses a critical public health threat, challenging the prevention and
treatment of bacterial infections. The search for innovative antibacterial agents has spurred …

Non-alcoholic fatty liver disease (NAFLD) is a health concern affecting 24% of the
population worldwide. Although the pathophysiologic mechanisms underlying disease are …

Age-related cognitive decline is the major cause of concern due to its 70% more incidence
than dementia cases worldwide. Moreover, aging is also the major risk factor of Alzheimer's …

Introduction The infections by multidrug-resistant bacteria are a growing threat to human
health, and the efficacy of the available antibiotics is gradually decreasing. As such, new …

Parkinson's disease (PD) is an incurable neurodegenerative movement disorder. PD affects
2% of the population above 65 years old; however, with the growing number of senior …

Increased oxidative stress (OS) and depletion of nigrostriatal dopamine (DA) are closely
linked to the neurodegeneration observed in Parkinson's Disease (PD). Caffeic acid (CA) …

Mitochondria are key organelles involved in cellular survival, differentiation, and death
induction. In this regard, mitochondrial morphology and/or function alterations are involved …

Although the lipophilic triphenylphosphonium (TPP+) cation is widely used to target
antioxidants to mitochondria, TPP+-based derivatives have shown cytotoxicity in several …