Development of type 2 diabetes mellitus in people with intermediate hyperglycaemia

B Richter, B Hemmingsen… - Cochrane Database …, 2018 - cochranelibrary.com
Background Intermediate hyperglycaemia (IH) is characterised by one or more
measurements of elevated blood glucose concentrations, such as impaired fasting glucose …

Advanced glycation end products: building on the concept of the “common soil” in metabolic disease

HH Ruiz, R Ramasamy, AM Schmidt - Endocrinology, 2020 - academic.oup.com
The role of advanced glycation end products (AGEs) in promoting and/or exacerbating
metabolic dysregulation is being increasingly recognized. AGEs are formed when reducing …

Circulating levels of AGEs and soluble RAGE isoforms are associated with all-cause mortality and development of cardiovascular complications in type 2 diabetes: a …

J Sabbatinelli, S Castiglione, F Macrì, A Giuliani… - Cardiovascular …, 2022 - Springer
Background Advanced glycation end-products (AGEs) and their interaction with the receptor
for advanced glycation end-products (RAGE) play a pivotal role in the development and …

Receptor for the Advanced Glycation End Products (RAGE) Pathway in Adipose Tissue Metabolism

K Gutowska, K Czajkowski, A Kuryłowicz - International journal of …, 2023 - mdpi.com
Advanced glycation end products (AGEs) are mediators in the process of cellular
dysfunction in response to hyperglycemia. Numerous data indicate that the accumulation of …

Accumulation of advanced glycation end products (AGEs) is associated with the severity of aortic stenosis in patients with concomitant type 2 diabetes

M Kopytek, M Ząbczyk, P Mazur, A Undas… - Cardiovascular …, 2020 - Springer
Background Accumulation of advanced glycation end products (AGEs) leads to chronic
glycation of proteins and tissue damage, particularly in patients with diabetes mellitus (DM) …

[HTML][HTML] Effects of an exercise-based lifestyle intervention on systemic markers of oxidative stress and advanced glycation endproducts in persons with type 2 diabetes …

GE Legaard, CS Feineis, MY Johansen… - Free Radical Biology …, 2022 - Elsevier
Aims/hypothesis This secondary analysis aimed to investigate the effects of a 12 months
intensive exercise-based lifestyle intervention on systemic markers of oxidative stress in …

[HTML][HTML] Implications of receptor for advanced glycation end products for progression from obesity to diabetes and from diabetes to cancer

A Garza-Campos, JR Prieto-Correa… - World journal of …, 2023 - ncbi.nlm.nih.gov
Obesity and type 2 diabetes mellitus (T2DM) are chronic pathologies with a high incidence
worldwide. They share some pathological mechanisms, including hyperinsulinemia, the …

The role of soluble receptor for advanced glycation end-products (sRAGE) in the general population and patients with diabetes mellitus with a focus on renal function …

M Steenbeke, S De Bruyne, M De Buyzere… - Critical Reviews in …, 2021 - Taylor & Francis
Isoforms of the receptor for advanced glycation end-product (RAGE) protein, which lack the
transmembrane and the signaling (soluble RAGE or sRAGE) domains are hypothesized to …

Crucial players in Alzheimer's disease and diabetes mellitus: friends or foes?

AM Kubis-Kubiak, A Rorbach-Dolata… - Mechanisms of Ageing …, 2019 - Elsevier
Alzheimer's disease (AD) and diabetes mellitus, especially type 2 (T2DM), are very common
and widespread diseases in contemporary societies, and their incidence is steadily on the …

[HTML][HTML] Modulation of soluble receptor for advanced glycation end-products (RAGE) isoforms and their ligands in healthy aging

F Scavello, F Zeni, CC Tedesco, E Mensà… - Aging (Albany …, 2019 - ncbi.nlm.nih.gov
The receptor for advanced glycation end-products (RAGE) recognizes several ligands
involved in inflammatory diseases. Two circulating soluble isoforms exist: esRAGE derived …