There is increasing evidence that inflammatory mechanisms other than eosinophilic
inflammation may be involved in producing the final common pathway of enhanced …

Background: Asthma is a chronic inflammatory airway disease that has a higher prevalence
in boys than in girls before puberty and a higher prevalence in women than in men in …

Objective: The authors sought to investigate the detection of non‐eosinophilic asthma using
induced sputum. Although this is an important subtype of clinical asthma, its recognition is …

Background Obesity and asthma are associated conditions; however, the mechanisms
linking the two remain unclear. Few studies have examined the effects of weight loss on …

Obesity and asthma are associated, but the mechanism (s) of the association have yet to be
elucidated. The aim of this study was to assess airway inflammation in relation to obesity …

Background The role of systemic inflammation in asthma is unclear. The aim of this study
was to compare systemic inflammation in subjects with stable asthma, categorized by airway …

Study objectives: To identify the characteristics of airway inflammation in persistent asthma
and to examine the role of neutrophilic inflammation in noneosinophilic persistent asthma …

Asthma is a chronic inflammatory disorder of the airways where bacteria may act as
protagonists of chronic inflammation. Little is known about the relation of airway …

Background In asthma, the airway inflammatory phenotype influences clinical characteristics
and treatment response. Although induced sputum is the gold standard test for phenotyping …

Rationale: Patients with refractory asthma have persistent symptoms despite maximal
treatment with inhaled corticosteroids and long-acting bronchodilators. The availability of …