Glioblastoma: current status, emerging targets, and recent advances

A Thakur, C Faujdar, R Sharma, S Sharma… - Journal of Medicinal …, 2022 - ACS Publications
Glioblastoma (GBM) is a highly malignant brain tumor characterized by a heterogeneous
population of genetically unstable and highly infiltrative cells that are resistant to …

[HTML][HTML] EphA2 in cancer: molecular complexity and therapeutic opportunities

L Toracchio, M Carrabotta, C Mancarella… - International Journal of …, 2024 - mdpi.com
Erythropoietin-producing hepatocellular A2 (EphA2) is a member of the Eph tyrosine kinase
receptor family that has been linked to various biological processes. In tumors, EphA2 …

Ephrin receptor type-A2 (EphA2) targeting in cancer: a patent review (2018–present)

M Tognolini, FR Ferrari, A Zappia… - Expert Opinion on …, 2024 - Taylor & Francis
Introduction EphA2 is a tyrosine kinase receptor and is considered a promising target in
cancer. Different approaches are used to target EphA2 receptor, and a lot of preclinical data …

Unveiling the therapeutic promise of EphA2 in glioblastoma: a comprehensive review

C Qiu, N Sun, S Zeng, L Chen, F Gong, J Tian… - Discover Oncology, 2024 - Springer
Glioblastoma (GBM), a primary brain tumor, exhibits remarkable invasiveness and is
characterized by its intricate location, infiltrative behavior, the presence of both the blood …

Integrated analysis of potential pathways by which aloe-emodin induces the apoptosis of colon cancer cells

D Jiang, S Ding, Z Mao, L You, Y Ruan - Cancer Cell International, 2021 - Springer
Background Colon cancer is a malignant gastrointestinal tumour with high incidence,
mortality and metastasis rates worldwide. Aloe-emodin is a monomer compound derived …

The mechanism of aloe-emodin in the treatment of colon cancer based on network pharmacological analysis

D Jiang, S Ding, Z Mao, L You - 2020 - researchsquare.com
Background: Colon cancer is a malignant gastrointestinal tumor with a high incidence, high
mortality and high metastasis in the world. Aloe-emodin is a monomer compound derived …