The interplay between toxoplasmosis and host miRNAs: Mechanisms and consequences

AS Doghish, MA Ali, MA Elrebehy, HH Mohamed… - … -Research and Practice, 2023 - Elsevier
Toxoplasmosis is one of the highly prevalent zoonotic diseases worldwide caused by the
parasite Toxoplasma gondii (T. gondii). The infection with T. gondii could pass unidentified …

Brains and brawn: toxoplasma infections of the central nervous system and skeletal muscle

EA Wohlfert, IJ Blader, EH Wilson - Trends in parasitology, 2017 - cell.com
Toxoplasma gondii is a widespread parasitic pathogen that infects over a third of the world's
population. Following an acute infection, the parasite can persist within its mammalian host …

Toxoplasmosis: a pathway to neuropsychiatric disorders

S Tyebji, S Seizova, AJ Hannan, CJ Tonkin - … & Biobehavioral Reviews, 2019 - Elsevier
Toxoplasma gondii is an obligate intracellular parasite that resides, in a latent form, in the
human central nervous system. Infection with Toxoplasma drastically alters the behaviour of …

Pathogenic infection in male mice changes sperm small RNA profiles and transgenerationally alters offspring behavior

S Tyebji, AJ Hannan, CJ Tonkin - Cell Reports, 2020 - cell.com
Germline epigenetic factors influence transgenerational inheritance of behavioral traits upon
changes in experience and environment. Immune activation due to infection can also …

Negative effects of latent toxoplasmosis on mental health

J Flegr, J Horáček - Frontiers in Psychiatry, 2020 - frontiersin.org
Infection by the parasite Toxoplasma, which affects about 33% of world population, is
associated with an increased risk of several mental health disorders, the most strongly with …

From inflammatory reactions to neurotransmitter changes: Implications for understanding the neurobehavioral changes in mice chronically infected with Toxoplasma …

T Wang, X Sun, W Qin, X Zhang, L Wu, Y Li… - Behavioural brain …, 2019 - Elsevier
Toxoplasma gondii is a protozoan parasite that can cause a latent infection in the central
nervous system, leading to neurobehavioral abnormalities in the host. However, the …

Toxoplasma infection induces microglia‐neuron contact and the loss of perisomatic inhibitory synapses

GL Carrillo, VA Ballard, T Glausen, Z Boone, J Teamer… - Glia, 2020 - Wiley Online Library
Infection and inflammation within the brain induces changes in neuronal connectivity and
function. The intracellular protozoan parasite, Toxoplasma gondii, is one pathogen that …

Toxoplasma gondii infection and the risk of adult glioma in two prospective studies

JM Hodge, AE Coghill, Y Kim, N Bender… - … journal of cancer, 2021 - Wiley Online Library
Toxoplasma gondii (T gondii) is a common parasite that shows affinity to neural tissue and
may lead to the formation of cysts in the brain. Previous epidemiologic studies have …

Estimations of the number people with mental diseases associated with toxoplasmosis and identification of risk factors by continent

J Nessim, JC Luna-Ramirez, GA Moreno-Gómez… - Psychiatry …, 2023 - Elsevier
Strong evidence exists based on metanalysis of the relationship between toxoplasmosis and
many psychiatric diseases: schizophrenia, bipolar disorder, and suicidal behavior. Herein …

Interaction between the complement system and infectious agents–a potential mechanistic link to neurodegeneration and dementia

N Shinjyo, W Kagaya, M Pekna - Frontiers in Cellular Neuroscience, 2021 - frontiersin.org
As part of the innate immune system, complement plays a critical role in the elimination of
pathogens and mobilization of cellular immune responses. In the central nervous system …