Cancer-and treatment-related cognitive dysfunction (CRCD) is a common challenge faced
by patients diagnosed with non-central nervous system (CNS) cancer. It has become …

Cancer-related cognitive impairment (CRCI) has increasingly been identified over the last
two decades in non-CNS system cancer patients. Across Europe, researchers have …

Methotrexate is a critical component of curative chemotherapy for pediatric acute
lymphoblastic leukemia (ALL), but is associated with neurotoxicity. Information on long‐term …

Background Although chemotherapy-induced leukoencephalopathy has been described in
case and cohort studies, literature remains inconclusive about its prevalence and …

Simple Summary In this study, we investigated standardized post-chemotherapy magnetic
resonance (MR) scans for leukoencephalopathy and patient-and treatment-related risk …

Background For children diagnosed with acute lymphoblastic leukemia (ALL), methotrexate
(MTX) treatment carries the risk of leukoencephalopathy and other treatment-related brain …

急性淋巴细胞白血病（ acute lymphoblastic leukemia， ALL） 是儿童期最常见的恶性肿瘤性疾病
。 随着临床诊治水平的不断提高， 获得完全缓解后长期生存的ALL 儿童越来越多 …

Background Previous case studies have provided evidence for chemotherapy-induced
leukoencephalopathy in patients with breast cancer. However, prospective research is …

Background Immune effector cell-associated neurotoxicity syndrome (ICANS) is a common
side-effect of chimeric antigen receptor T-cell (CAR-T) therapy, with symptoms ranging from …

Background Methotrexate is an essential medicine used to treat childhood malignancies
including acute lymphoblastic leukemia. Neurotoxicity manifesting as leukoencephalopathy …