Intestinal epithelial cells (IECs) serve as both a physical and an antimicrobial barrier against
the microbiota, as well as a conduit for signaling between the microbiota and systemic host …

The significance of diversity, composition, and functional attributes of the gut microbiota in
shaping human health is well recognized. Studies have shown that gut microbiota is closely …

Emerging new evidence highlights the importance of prolonged daily fasting periods for the
health and survival benefits of calorie restriction (CR) and time-restricted feeding (TRF) in …

Background Aging-related fertility decline is a prevalent concern globally. Male reproductive
system aging is mainly characterized by a decrease in sperm quality and fertility. While it is …

Growing evidence suggests a possible involvement of the intestinal microbiota in generating
new neurons, but a detailed breakdown of the microbiota composition is lacking. In this …

The gut microbiome impacts host health and fitness, in part through the diversification of gut
metabolic function and pathogen protection. Elevations in glucocorticoids (GCs) appear to …

Ageing, cellular senescence and chronic kidney disease: expe... : Current Opinion in Nephrology
and Hypertension Ageing, cellular senescence and chronic kidney disease: experimental …

Inulin, a soluble dietary fiber, is thought to exert multiple beneficiary effects through
promoting growth of bacteria that metabolize the fiber to short-chain fatty acids (SCFAs); …

Aging entails changes at the cellular level that increase the risk of various pathologies. An
association between gut microbiota and age-related diseases has also been attributed. This …

Nicotinamide riboside (NR) acts as a nicotinamide adenine dinucleotide (NAD+) precursor
where NR supplementation has previously been shown to be beneficial. Thus, we …