Role of salivary biomarkers in oral cancer detection

Z Khurshid, MS Zafar, RS Khan, S Najeeb… - Advances in clinical …, 2018 - Elsevier
Oral cancers are the sixth most frequent cancer with a high mortality rate. Oral squamous
cell carcinoma accounts for more than 90% of all oral cancers. Standard methods used to …

Review insights on salivary proteomics biomarkers in oral cancer detection and diagnosis

VR Umapathy, PM Natarajan, B Swamikannu - Molecules, 2023 - mdpi.com
Early detection is crucial for the treatment and prognosis of oral cancer, a potentially lethal
condition. Tumor markers are abnormal biological byproducts produced by malignant cells …

[HTML][HTML] Current aspects on oral squamous cell carcinoma

AK Markopoulos - The open dentistry journal, 2012 - ncbi.nlm.nih.gov
Oral squamous cell carcinoma is the most common malignant epithelial neoplasm affecting
the oral cavity. This article overviews the essential points of oral squamous cell carcinoma …

Changes in abundance of oral microbiota associated with oral cancer

BL Schmidt, J Kuczynski, A Bhattacharya, B Huey… - PloS one, 2014 - journals.plos.org
Individual bacteria and shifts in the composition of the microbiome have been associated
with human diseases including cancer. To investigate changes in the microbiome …

The challenges of OSCC diagnosis: salivary cytokines as potential biomarkers

A Roi, CI Roi, ML Negruțiu, M Riviș… - Journal of clinical …, 2020 - mdpi.com
Fast, economic, and noninvasive, molecular analysis of saliva has the potential to become a
diagnostic tool of reference for several local and systemic diseases, oral cancer included …

Recent advances in graphene-based nanobiosensors for salivary biomarker detection

R Goldoni, M Farronato, ST Connelly… - Biosensors and …, 2021 - Elsevier
As biosensing research is rapidly advancing due to significant developments in materials,
chemistry, and electronics, researchers strive to build cutting-edge biomedical devices …

Oral cancers: current status

AK D'Cruz, R Vaish, H Dhar - Oral oncology, 2018 - Elsevier
Oral cancer is a global disease. Despite a well elucidated tumour progression model, these
cancers present late. Attempts at early detection by way of adjunctive diagnostic …

Emerging biosensors for oral cancer detection and diagnosis—A review unravelling their role in past and present advancements in the field of early diagnosis

VR Umapathy, PM Natarajan, B Swamikannu, J Moses… - Biosensors, 2022 - mdpi.com
Oral cancer is a serious concern to people all over the world because of its high mortality
rate and metastatic spread to other areas of the body. Despite recent advancements in …

Insights into immune responses in oral cancer through proteomic analysis of saliva and salivary extracellular vesicles

FV Winck, AC Prado Ribeiro, R Ramos Domingues… - Scientific reports, 2015 - nature.com
The development and progression of oral cavity squamous cell carcinoma (OSCC) involves
complex cellular mechanisms that contribute to the low five-year survival rate of …

Salivary biomarkers in oral squamous cell carcinoma–An insight

T Radhika, N Jeddy, S Nithya… - Journal of oral biology …, 2016 - Elsevier
Oral cancer refers to the malignancies that occur in the oral cavity, lip and pharynx with 90%
of oral cancers being squamous cell carcinomas (OSCC). OSCC has the highest mortality …