The activities of HIV‐1 in the central nervous system (CNS) are responsible for a
dysregulated neuroinflammatory response and the subsequent development of HIV …

A central aspect of nervous system development and function is the post-transcriptional
regulation of mRNA fate, which implies time-and site-dependent translation, in response to …

People living with HIV (PLH) have significantly higher rates of cognitive impairment (CI) and
major depressive disorder (MDD) versus the general population. The enzyme neutral …

Background HIV can invade the central nervous system (CNS) early during infection,
invading perivascular macrophages and microglia, which, in turn, release viral particles and …

Introduction Exposure to maternal HIV in pregnancy may be a risk factor for impaired child
neurodevelopment during the first years of life. Altered neurometabolites have been …

People living with HIV (PLHIV) are known to be at a higher risk of developing an array of
aging-related diseases despite well-adhered combined antiretroviral therapy (cART). The …

Background Myelin oligodendrocyte glycoprotein (MOG) antibody-associated disease
(MOGAD) is an autoimmune demyelinating disorder of the central nervous system. Methods …

State-of-the-art liquid chromatography/mass spectrometry (LC/MS)-based proteomic
technologies, using microliter amounts of patient plasma, can detect and quantify several …

HIV-associated neurocognitive disorder (HAND) is a major neurological complication of HIV.
The diagnosis of HAND is done through clinical assessment and exclusion of other potential …

Disturbances in lipid metabolism in the CNS contribute to neurodegeneration and cognitive
impairments. Through tight metabolic coupling, astrocytes provide energy to neurons by …