Genetics of diffuse large B-cell lymphoma

L Pasqualucci, R Dalla-Favera - Blood, The Journal of the …, 2018 - ashpublications.org
Diffuse large B-cell lymphoma (DLBCL), the most frequent subtype of lymphoid malignancy,
remains a significant clinical challenge, as∼ 30% of patients are not cured. Over the past …

Adhesion receptors of the immune system

TA Springer - Nature, 1990 - nature.com
The adhesive interactions of cells with other cells and with the extracellular matrix are crucial
to all developmental processes, but have a central role in the functions of the immune …

Analysis of the coding genome of diffuse large B-cell lymphoma

L Pasqualucci, V Trifonov, G Fabbri, J Ma, D Rossi… - Nature …, 2011 - nature.com
Diffuse large B-cell lymphoma (DLBCL) is the most common form of human lymphoma.
Although a number of structural alterations have been associated with the pathogenesis of …

IFN signaling and neutrophil degranulation transcriptional signatures are induced during SARS-CoV-2 infection

BA Rosa, M Ahmed, DK Singh… - Communications …, 2021 - nature.com
SARS-CoV-2 virus has infected more than 92 million people worldwide resulting in the
Coronavirus disease 2019 (COVID-19). Using a rhesus macaque model of SARS-CoV-2 …

Regulation of immune responses and chronic inflammation by fibroblast-like synoviocytes

H Yoshitomi - Frontiers in immunology, 2019 - frontiersin.org
Synovial tissue is a membranous non-immune organ lining joint cavities where it supports
local immune responses, and functions directly and indirectly in joint destruction due to …

Recognition of cluster of differentiation 1 antigens by human CD4CD8>− cytolytic T lymphocyte

S Porcelli, MB Brenner, JL Greenstein, C Terhorst… - Nature, 1989 - nature.com
Abstract HUMAN cluster-of-differentiation 1 (CD1) is a family of cell surface glycoproteins of
unknown function expressed on immature thymocytes, epidermal Langerhans cells and a …

The structure and ligand interactions of CD2: implications for T-cell function

SJ Davis, PA Van Der Merwe - Immunology today, 1996 - cell.com
The protein-protein interaction underlying l&and recogmtion by CD2 must ensure sprcifuty
while allowing for wry weak binding. The CD5Rbmdmg site on human CD2 has nuw brrn …

Adhesion molecule expression and regulation on cells of the central nervous system

SJ Lee, EN Benveniste - Journal of neuroimmunology, 1999 - Elsevier
Cellular adhesion molecules were initially defined as cell surface structures mediating cell–
cell and cell–extracellular matrix (ECM) interactions. Adhesion molecules involved in …

Destructive roles of fibroblast-like synoviocytes in chronic inflammation and joint damage in rheumatoid arthritis

M Masoumi, H Bashiri, H Khorramdelazad… - Inflammation, 2021 - Springer
Fibroblast-like synoviocytes (FLSs) are important non-immune cells located mostly in the
inner layer of the synovium. Indeed, these cells are specialized mesenchymal cells …

Synovial fibroblasts in 2017

C Ospelt - RMD open, 2017 - rmdopen.bmj.com
Stromal cells like synovial fibroblasts gained great interest over the years, since it has
become clear that they strongly influence their environment and neighbouring cells. The …