The rapid development of new generation sequencing technology has deepened the
understanding of genomes and functional products. RNA-sequencing studies in mammals …

Recent experimental evidence indicates that lncRNAs can act as regulatory molecules in the
context of development and disease. Xist, the master regulator of X chromosome …

The combination of high-throughput sequencing and in vivo crosslinking approaches leads
to the progressive uncovering of the complex interdependence between cellular …

Motivation The secondary structure of RNA is of importance to its function. Over the last few
years, several papers attempted to use machine learning to improve de novo RNA …

Specific elements of viral genomes regulate interactions within host cells. Here, we
calculated the secondary structure content of> 2000 coronaviruses and computed> 100 000 …

The long non-coding RNA Xist induces heterochromatinization of the X chromosome by
recruiting repressive protein complexes to chromatin. Here we gather evidence, from the …

HOTAIR is a lncRNA overexpressed in several epithelial cancers and strongly correlated
with invasion. This lncRNA was proven a pivotal element of the epithelial-to-mesenchymal …

Medicines based on messenger RNA (mRNA) hold immense potential, as evidenced by
their rapid deployment as COVID-19 vaccines. However, worldwide distribution of mRNA …

Despite the popularity of computer-aided study and design of RNA molecules, little is known
about the accuracy of commonly used structure modeling packages in tasks sensitive to …

The three-dimensional structure of RNA molecules plays a critical role in a wide range of
cellular processes encompassing functions from riboswitches to epigenetic regulation …