Epigenetic alterations in colorectal cancer: emerging biomarkers

Y Okugawa, WM Grady, A Goel - Gastroenterology, 2015 - Elsevier
Colorectal cancer (CRC) is a leading cause of cancer deaths worldwide. One of the
fundamental processes driving the initiation and progression of CRC is the accumulation of …

Competing endogenous RNA (ceRNA) cross talk and language in ceRNA regulatory networks: a new look at hallmarks of breast cancer

R Abdollahzadeh, A Daraei, Y Mansoori… - Journal of cellular …, 2019 - Wiley Online Library
Breast cancer (BC) is the most frequently occurring malignancy in women worldwide.
Despite the substantial advancement in understanding the molecular mechanisms and …

Ketogenic diet in cancer prevention and therapy: molecular targets and therapeutic opportunities

WH Talib, AI Mahmod, A Kamal, HM Rashid… - Current issues in …, 2021 - mdpi.com
Although cancer is still one of the most significant global challenges facing public health, the
world still lacks complementary approaches that would significantly enhance the efficacy of …

lincRNA-RoR and miR-145 regulate invasion in triple-negative breast cancer via targeting ARF6

G Eades, B Wolfson, Y Zhang, Q Li, Y Yao… - Molecular Cancer …, 2015 - AACR
Abstract Triple-negative (ER−, HER2−, PR−) breast cancer (TNBC) is an aggressive disease
with a poor prognosis with no available molecularly targeted therapy. Silencing of microRNA …

The role of microRNAs in colorectal cancer

AJ Schetter, H Okayama, CC Harris - The Cancer Journal, 2012 - journals.lww.com
During the last decade, it has become clear that aberrant microRNA expression has a
functional role in the initiation and progression of colorectal cancer (CRC). Specific …

MiR-145 directly targets p70S6K1 in cancer cells to inhibit tumor growth and angiogenesis

Q Xu, LZ Liu, X Qian, Q Chen, Y Jiang, D Li… - Nucleic acids …, 2012 - academic.oup.com
MiR-145 can regulate cell apoptosis, proliferation, neural development and stem cell
differentiation. Previous studies indicate that miR-145 is downregulated in human colon …

Lessons from miR-143/145: the importance of cell-type localization of miRNAs

OA Kent, MN McCall, TC Cornish… - Nucleic acids …, 2014 - academic.oup.com
Abstract miR-143 and miR-145 are co-expressed microRNAs (miRNAs) that have been
extensively studied as potential tumor suppressors. These miRNAs are highly expressed in …

Salivary micro RNA s in oral cancer

F Zahran, D Ghalwash, O Shaker, K Al‐Johani… - Oral …, 2015 - Wiley Online Library
Objective This study investigated the use of three salivary micro RNA s (mi RNA‐21, mi RNA‐
184, and mi RNA‐145) as possible markers for malignant transformation in oral mucosal …

MicroRNAs associated with metastatic prostate cancer

A Watahiki, Y Wang, J Morris, K Dennis, HM O'Dwyer… - PloS one, 2011 - journals.plos.org
Objective Metastasis is the most common cause of death of prostate cancer patients.
Identification of specific metastasis biomarkers and novel therapeutic targets is considered …

miR-21 and miR-145 cooperation in regulation of colon cancer stem cells

Y Yu, P Nangia-Makker, L Farhana, S G. Rajendra… - Molecular cancer, 2015 - Springer
Background Acquired drug resistance is one of the major reasons for failing cancer
therapies. Although the reasons are not fully understood, they may be related to the …