Near-infrared fluorophores for biomedical imaging

G Hong, AL Antaris, H Dai - Nature biomedical engineering, 2017 - nature.com
In vivo near-infrared (NIR) fluorescence imaging is an emerging biomedical imaging
modality for use in both fundamental scientific research and clinical practice. Owing to …

Dynamic Tracking of Biological Processes Using Near-Infrared Fluorescent Single-Walled Carbon Nanotubes

S Basu, A Hendler-Neumark… - ACS Applied Materials & …, 2024 - ACS Publications
Biological processes are characterized by dynamic and elaborate temporal patterns driven
by the interplay of genes, proteins, and cellular components that are crucial for adaptation to …

Carbon-Dot-Decorated Carbon Nitride Nanoparticles for Enhanced Photodynamic Therapy against Hypoxic Tumor via Water Splitting

DW Zheng, B Li, CX Li, JX Fan, Q Lei, C Li, Z Xu… - ACS …, 2016 - ACS Publications
Hypoxia, a typical feature of solid tumors, remarkably restricts the efficiency of photodynamic
therapy (PDT). Here, a carbon nitride (C3N4)-based multifunctional nanocomposite (PCCN) …

An optical nanoreporter of endolysosomal lipid accumulation reveals enduring effects of diet on hepatic macrophages in vivo

TV Galassi, PV Jena, J Shah, G Ao, E Molitor… - Science translational …, 2018 - science.org
The abnormal accumulation of lipids within the endolysosomal lumen occurs in many
conditions, including lysosomal storage disorders, atherosclerosis, nonalcoholic fatty liver …

Creating fluorescent quantum defects in carbon nanotubes using hypochlorite and light

CW Lin, SM Bachilo, Y Zheng, U Tsedev… - Nature …, 2019 - nature.com
Covalent doping of single-walled carbon nanotubes (SWCNTs) can modify their optical
properties, enabling applications as single-photon emitters and bio-imaging agents. We …

Near-infrared emitting graphene quantum dots synthesized from reduced graphene oxide for in vitro/in vivo/ex vivo bioimaging applications

MT Hasan, BH Lee, CW Lin, A McDonald-Boyer… - 2D …, 2021 - iopscience.iop.org
Near-infrared (NIR) emissive nanomaterials are desired for bioimaging and drug delivery
applications due to the high tissue penetration depth of NIR light, enabling in vitro/ex vivo/in …

Deep-tissue optical imaging of near cellular-sized features

X Dang, NM Bardhan, J Qi, L Gu, NA Eze, CW Lin… - Scientific reports, 2019 - nature.com
Detection of biological features at the cellular level with sufficient sensitivity in complex
tissue remains a major challenge. To appreciate this challenge, this would require finding …

Understanding the Molecular Assemblies of Single Walled Carbon Nanotubes and Tailoring their Photoluminescence for the Next-Generation Optical Nanosensors

N Sultana, HM Dewey, AG Arellano… - Chemistry of …, 2024 - ACS Publications
Interest in optical materials for biomedical imaging and sensing applications has grown
significantly in recent decades. Among a variety of material choices, single-walled carbon …

Surface plasmon enhanced upconversion fluorescence in short-wave infrared for in vivo imaging of ovarian cancer

CW Lin, S Huang, M Colangelo, C Chen, FNC Wong… - Acs Nano, 2022 - ACS Publications
Short-wave infrared (SWIR; 850–1700 nm) upconversion fluorescence enables
“autofluorescence-free” imaging with minimal tissue scattering, yet it is rarely explored due …

Surface Plasmon‐Enhanced Short‐Wave Infrared Fluorescence for Detecting Sub‐Millimeter‐Sized Tumors

S Huang, CW Lin, J Qi, AM Iyer, Y He, Y Li… - Advanced …, 2021 - Wiley Online Library
Abstract Short‐wave infrared (SWIR, 900–1700 nm) enables in vivo imaging with high
spatiotemporal resolution and penetration depth due to the reduced tissue autofluorescence …