Stroke is a major cause of mortality and disability globally, with ischemic stroke (IS)
accounting for over 80% of all stroke cases. The pathological process of IS involves …

Cerebral small vessel disease (CSVD) encompasses a broad clinical spectrum united by
pathology of the small vessels of the brain. CSVD is commonly identified using brain …

Epigenetic alterations affect the onset of ischemic stroke, brain injury after stroke, and
mechanisms of poststroke recovery. In particular, DNA methylation can be dynamically …

The role of chromatin biology and epigenetics in disease progression is gaining increasing
recognition. Genes that escape X chromosome inactivation (XCI) can impact …

To investigate the effect of rapamycin on mitochondrial dynamic balance in diabetic rats
subjected to cerebral ischemia-reperfusion injury. Male Sprague Dawley (SD) rats (n= 78) …

ABSTRACT Background Globally, individuals of African ancestry have a relatively greater
stroke preponderance compared to other racial/ethnic groups. The higher prevalence of …

Cerebrovascular diseases, especially stroke, are critical and heterogenous clinical
conditions associated with high mortality and chronic disability. Genome-wide association …

Acute ischemic stroke is one of the diseases causing death worldwide. MicroRNAs have
pivotal roles in acute ischemic stroke pathogenesis, and their expression dysregulation …

We aimed to unveil the clinical significance of serum 25-hydroxyvitamin D (25-OH-VD),
insulin-like growth factor 1 (IGF-1), and beta-2 microglobulin (β2-MG) levels in cognitive …

Despite decreases in overall stroke incidence and mortality in the United States, racial and
ethnic disparities continue unabated. Of note, the long-standing disproportionate burden of …