[HTML][HTML] Diagnostics for COVID-19: moving from pandemic response to control

RW Peeling, DL Heymann, YY Teo, PJ Garcia - The Lancet, 2022 - thelancet.com
Diagnostics have proven to be crucial to the COVID-19 pandemic response. There are three
major methods for the detection of SARS-CoV-2 infection and their role has evolved during …

Antibody-mediated neutralization of SARS-CoV-2

H Gruell, K Vanshylla, T Weber, CO Barnes, C Kreer… - Immunity, 2022 - cell.com
Neutralizing antibodies can block infection, clear pathogens, and are essential to provide
long-term immunity. Since the onset of the pandemic, SARS-CoV-2 neutralizing antibodies …

Omicron BA. 1 breakthrough infection drives cross-variant neutralization and memory B cell formation against conserved epitopes

J Quandt, A Muik, N Salisch, BG Lui, S Lutz… - Science …, 2022 - science.org
Omicron is the evolutionarily most distinct severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) variant of concern (VOC) to date. We report that Omicron BA. 1 breakthrough …

Three exposures to the spike protein of SARS-CoV-2 by either infection or vaccination elicit superior neutralizing immunity to all variants of concern

PR Wratil, M Stern, A Priller, A Willmann, G Almanzar… - Nature medicine, 2022 - nature.com
Infection-neutralizing antibody responses after severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) infection or coronavirus disease 2019 vaccination are an …

Dynamics of antibody response to BNT162b2 vaccine after six months: a longitudinal prospective study

P Naaber, L Tserel, K Kangro, E Sepp… - The Lancet Regional …, 2021 - thelancet.com
ABSTRACT Background SARS-CoV-2 mRNA vaccines have proven high efficacy, however,
limited data exists on the duration of immune responses and their relation to age and side …

Neutralizing antibody levels are highly predictive of immune protection from symptomatic SARS-CoV-2 infection

DS Khoury, D Cromer, A Reynaldi, TE Schlub… - Nature medicine, 2021 - nature.com
Predictive models of immune protection from COVID-19 are urgently needed to identify
correlates of protection to assist in the future deployment of vaccines. To address this, we …

Impact of vaccination on new SARS-CoV-2 infections in the United Kingdom

E Pritchard, PC Matthews, N Stoesser, DW Eyre… - Nature medicine, 2021 - nature.com
The effectiveness of COVID-19 vaccination in preventing new severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) infections in the general community is still unclear …

SARS-CoV-2-specific T cells in infection and vaccination

A Bertoletti, N Le Bert, M Qui, AT Tan - Cellular & molecular …, 2021 - nature.com
During viral infections, antibodies and T cells act together to prevent pathogen spread and
remove virus-infected cells. Virus-specific adaptive immunity can, however, also trigger …

Humoral and cellular immune responses to two and three doses of SARS-CoV-2 vaccines in rituximab-treated patients with rheumatoid arthritis: a prospective, cohort …

I Jyssum, H Kared, TT Tran, AT Tveter… - The Lancet …, 2022 - thelancet.com
Background In rituximab-treated patients with rheumatoid arthritis, humoral and cellular
immune responses after two or three doses of SARS-CoV-2 vaccines are not well …

Long-term SARS-CoV-2-specific immune and inflammatory responses in individuals recovering from COVID-19 with and without post-acute symptoms

MJ Peluso, AN Deitchman, L Torres, NS Iyer… - Cell Reports, 2021 - cell.com
We describe severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-specific T cell
responses, soluble markers of inflammation, and antibody levels and neutralization capacity …