Cytoreductive conditioning regimens used in the context of allogeneic hematopoietic cell
transplantation (HCT) elicit deficits in innate and adaptive immunity, which predispose …

The innate immune system comprises a collection of cells that recognize and eradicate
pathogens or aberrant cells without priming or antigen presentation. Natural killer cells …

Umbilical cord blood (UCB) is an alternative source of hematopoietic stem cells for patients
without HLA-matched adult donors. UCB contains a low number of nucleated cells and …

Hematopoietic stem-cell transplantation is associated with a profound immune deficiency
manifested as an increased propensity to develop infections and probably also …

Hematopoietic stem cell transplantation (HSCT) is an effective treatment option for several
malignant and non-malignant hematological diseases. The clinical outcome of this …

As an important treatment for acute myeloid leukemia, allogeneic hematopoietic stem cell
transplantation (allo-HSCT) plays an important role in reducing relapse and improving long …

Complete donor chimerism is strongly associated with complete remission after allogeneic
stem cell transplantation (allo-SCT) in patients with hematologic malignancies. Donor …

Here we investigated the influence of parameters known before hematopoietic stem cell
transplantation (HSCT) as well as the relevance of graft-versus-host disease (GvHD) and …

Recipient-specific regulatory T cells (rsTreg) can prevent graft-versus-host disease (GVHD)
by inhibiting donor T-cell expansion after hematopoietic stem cell transplantation (HSCT) in …

Immune reconstitution appears to be delayed following myeloablative conditioning (MAC)
and umbilical cord blood transplantation (UCBT) in paediatric recipients. Although reduced …