Breast cancer is the most common malignancy in women worldwide. Metastasis is the
leading cause of high mortality in most cancers. Although predicting the early stage of breast …

Natural killer (NK) cells are the predominant innate lymphocyte subsets that mediate anti-
tumor and anti-viral responses, and therefore possess promising clinical utilization. NK cells …

Background Metastasis of breast cancer have caused the majority of cancer-related death
worldwide. The circRNAs are associated with tumorigenesis and metastasis in breast cancer …

The epithelial-to-mesenchymal transition (EMT) plays a critical role during normal
development and in cancer progression. EMT is induced by various signaling pathways …

Similar to embryonic development, changes in cell phenotypes defined as an epithelial to
mesenchymal transition (EMT) have been shown to play a role in the tumorigenic process …

Inflammasomes are molecular platforms that assemble upon sensing various intracellular
stimuli. Inflammasome assembly leads to activation of caspase 1, thereby promoting the …

Cancer-associated fibroblasts (CAFs) are critical components of the tumor microenvironment
(TME) with diverse functions such as extracellular matrix (ECM) remodeling, modulation of …

Metastasis, the dissemination of cancer cells from primary tumors, represents a major hurdle
in the treatment of cancer. The epithelial-mesenchymal transition (EMT) has been studied in …

There is highly credible evidence that melatonin mitigates cancer at the initiation,
progression and metastasis phases. In many cases, the molecular mechanisms …

Metastasis, the spread of cancer from a primary site to distant organs, is an important
challenge in oncology. This Review explores the complexities of immune escape …