TRIF-dependent signaling and its role in liver diseases

L Hu, Z Cheng, H Chu, W Wang, Y Jin… - Frontiers in Cell and …, 2024 - frontiersin.org
TIR domain-containing adaptor inducing IFN-β (TRIF) is a crucial adaptor molecule
downstream of toll-like receptors 3 (TLR3) and 4 (TLR4). TRIF directly binds to TLR3 through …

Targeting Bacteria‐Induced Ferroptosis of Bone Marrow Mesenchymal Stem Cells to Promote the Repair of Infected Bone Defects

K Yuan, Y Yang, Y Lin, F Zhou, K Huang… - Advanced …, 2024 - Wiley Online Library
The specific mechanisms underlying bacteria‐triggered cell death and osteogenic
dysfunction in host bone marrow mesenchymal stem cells (BMSCs) remain unclear, posing …

Bispecific antibodies tethering innate receptors induce human tolerant-dendritic cells and regulatory T cells

L Lamendour, M Gilotin… - Frontiers in …, 2024 - frontiersin.org
There is an urgent need for alternative therapies targeting human dendritic cells (DCs) that
could reverse inflammatory syndromes in many autoimmune and inflammatory diseases and …

The Application of Cinnamon Twig Extract as an Inhibitor of Listeriolysin O against Listeria monocytogenes Infection

X Hou, Q Sheng, J Zhang, R Du, N Wang, H Zhu… - Molecules, 2023 - mdpi.com
As a major virulence factor of Listeria monocytogenes (L. monocytogenes), listeriolysin O
(LLO) can assist in the immune escape of L. monocytogenes, which is critical for the …

Proteomics analysis of PK-15 cells infected with porcine parvovirus and the effect of PCBP1 on PPV replication

L Wang, Y Song, M Xu, C Zhang, L Zhang… - Microbiology …, 2024 - Am Soc Microbiol
Porcine parvovirus (PPV) is one of the most important pathogens that cause reproductive
failure in pigs. However, the pathogenesis of PPV infection remains unclear. Proteomics is a …

Neutrophil-to-Lymphocyte Ratio (NLR), Platelet-to-Lymphocyte Ratio (PLR) and Monocyte-to-Lymphocyte Ratio (MLR) as Biomarkers in Diagnosis Evaluation of Acute …

C Cai, W Zeng, H Wang, S Ren - International Journal of Chronic …, 2024 - Taylor & Francis
Purpose Hierarchical management is advocated in China to effectively manage chronic
obstructive pulmonary disease (COPD) patients and reduce the incidence and mortality of …

Characterization of the host-mediated modification of bacterial effector NleA

L Burns - 2024 - escholarship.mcgill.ca
Escherichia coli is a ubiquitous member of the human intestinal microbiota. Although
commensal E. coli and its human host generally coexist with mutual benefits in digestion …

Editorial on proteases in health and disease

B Turk - Molecular aspects of medicine, 2022 - pubmed.ncbi.nlm.nih.gov

Expression and clinical significance of Toll-like receptor 4 on peripheral blood CD14+ monocytes of patients with secondary haemophagocytic lymphohistiocytosis

T Tian, J Wang, X Gao, G Yin, J Xu, H Qiu, L Duan - 2023 - researchsquare.com
Background Secondary haemophagocytic lymphohistiocytosis (sHLH) develops
predominantly in adulthood and is triggered by a number of factors, with a lack of reliable …