Molecular genetic of human male infertility: from genes to new therapeutic perspectives

PH Vogt - Current pharmaceutical design, 2004 - ingentaconnect.com
Genetic lesions causing human male infertility are manifold. Besides gross chromosomal
aneuploidies and rearrangements, microdeletions and single gene defects can interfere with …

Male infertility

E Iammarrone, R Balet, AM Lower, C Gillott… - Best practice & research …, 2003 - Elsevier
Infertility affects 13–18% of couples and growing evidence from clinical and epidemiological
studies suggests an increasing incidence of male reproductive problems. The pathogenesis …

[HTML][HTML] Use of surgical sperm retrieval in azoospermic men: a meta-analysis

JDM Nicopoullos, C Gilling-Smith, PA Almeida… - Fertility and …, 2004 - Elsevier
OBJECTIVE: To compare the outcomeof intracytoplasmic sperm injection (ICSI) cycles [1]
using epididymal and testicular sperm in patients with obstructive azoospermia (OA);[2] …

Sperm defect severity rather than sperm source is associated with lower fertilization rates after intracytoplasmic sperm injection

S Verza Jr, SC Esteves - International braz j urol, 2008 - SciELO Brasil
OBJECTIVE: To evaluate the impact of sperm defect severity and the type of azoospermia on
the outcomes of intracytoplasmic sperm injection (ICSI). MATERIALS AND METHODS: This …

Non-Obstructive Azoospermia and Intracytoplasmic Sperm Injection: Unveiling the Chances of Success and Possible Consequences for Offspring

A Majzoub, MC Viana, APP Achermann… - Journal of Clinical …, 2024 - pmc.ncbi.nlm.nih.gov
Non-obstructive azoospermia (NOA) is found in up to 15% of infertile men. While several
causes for NOA have been identified, the exact etiology remains unknown in many patients …

Testicular sperm is superior to ejaculated sperm for ICSI in cryptozoospermia: an update systematic review and meta-analysis

YN Kang, YW Hsiao, CY Chen, CC Wu - Scientific Reports, 2018 - nature.com
Intracytoplasmic sperm injection (ICSI) is well established and provides patients with
severely impaired sperm quality with an opportunity to father a child. However, previous …

[HTML][HTML] Does the outcome of ICSI in cases of obstructive azoospermia depend on the origin of the retrieved spermatozoa or the cause of obstruction? A comparative …

A Kamal, I Fahmy, R Mansour, G Serour, M Aboulghar… - Fertility and sterility, 2010 - Elsevier
OBJECTIVE: To compare the outcomes of intracytoplasmic sperm injection (ICSI) for men
with obstructive azoospermia and normal spermatogenesis, according to the use of …

ICSI outcomes in obstructive azoospermia: influence of the origin of surgically retrieved spermatozoa and the cause of obstruction

C Buffat, C Patrat, F Merlet, J Guibert… - Human …, 2006 - academic.oup.com
BACKGROUND: Spermatozoa can be retrieved from the testis and epididymis of men with
obstructive azoospermia (OA) and used for ICSI. However, it is unknown whether the …

Paternal effects on early embryogenesis

L Nanassy, DT Carrell - Journal of Experimental & Clinical Assisted …, 2008 - Springer
Historically, less attention has been paid to paternal effects on early embryogenesis than
maternal effects. However, it is now apparent that certain male factor infertility phenotypes …

Decreased sperm motility retarded ICSI fertilization rate in severe oligozoospermia but good-quality embryo transfer had achieved the prospective clinical outcomes

J Zheng, Y Lu, X Qu, P Wang, L Zhao, M Gao, H Shi… - PloS one, 2016 - journals.plos.org
Introduction Spermatozoa motility is the critical parameter to affect the treatment outcomes
during assisted reproductive technologies (ART), but its reproductive capability remains a …