Nuclear magnetic resonance (NMR) spectroscopy is an important analytical technique in
metabolomics. Because it provides atomic-level detail of small molecules, NMR is …

As investigators decipher the underlining mechanisms of Staphylococcus aureus
pathogenesis, it is becoming apparent that perturbations in central metabolism alter …

Purines and their derivatives control intracellular energy homeostasis and nucleotide
synthesis, and act as signaling molecules. Here, we combine structural and sequence …

Background Vibrio scophthalmi is an opportunistic bacterial pathogen, which is widely
distributed in the marine environment. Earlier studies have suggested that it is a normal …

Staphylococcus aureus (SA) is an opportunistic pathogen that can cause a wide spectrum of
infections, from superficial skin inflammation to severe and potentially fatal and invasive …

The colonizing microbiota on the body surface play a crucial role in barrier function.
Staphylococcus aureus (S. aureus) is a significant contributor to skin infection, and the …

Resistance to antibiotics is an increasing problem and necessitates novel antibacterial
therapies. The polyketide antibiotics cervimycin A to D are natural products of Streptomyces …

Environmental acidification impairs microorganism diversity and their functions on
substance transformation. Rhodococcus is a ubiquitously distributed genus for contaminant …

Invasion and persistence of bacteria within host cells requires that they adapt to life in an
intracellular environment. This adaptation induces bacterial stress through events such as …

Cervimycins A–D are bis-glycosylated polyketide antibiotics produced by Streptomyces
tendae HKI 0179 with bactericidal activity against Gram-positive bacteria. In this study …