Multi-omics research strategies in ischemic stroke: A multidimensional perspective
W Li, C Shao, H Zhou, H Du, H Chen, H Wan… - Ageing Research …, 2022 - Elsevier
Ischemic stroke (IS) is a multifactorial and heterogeneous neurological disorder with high
rate of death and long-term impairment. Despite years of studies, there are still no stroke …
rate of death and long-term impairment. Despite years of studies, there are still no stroke …
Body fluid multiomics in 3PM-guided ischemic stroke management: health risk assessment, targeted protection against health-to-disease transition, and cost-effective …
R Chen, X Wang, N Li, O Golubnitschaja, X Zhan - EPMA Journal, 2024 - Springer
Because of its rapid progression and frequently poor prognosis, stroke is the third major
cause of death in Europe and the first one in China. Many independent studies …
cause of death in Europe and the first one in China. Many independent studies …
ANPELA: analysis and performance assessment of the label-free quantification workflow for metaproteomic studies
Label-free quantification (LFQ) with a specific and sequentially integrated workflow of
acquisition technique, quantification tool and processing method has emerged as the …
acquisition technique, quantification tool and processing method has emerged as the …
Simultaneous improvement in the precision, accuracy, and robustness of label-free proteome quantification by optimizing data manipulation chains*[S]
The label-free proteome quantification (LFQ) is multistep workflow collectively defined by
quantification tools and subsequent data manipulation methods that has been extensively …
quantification tools and subsequent data manipulation methods that has been extensively …
Multi-omics approaches to improve malaria therapy
Malaria contributes to the most widespread infectious diseases worldwide. Even though
current drugs are commercially available, the ever-increasing drug resistance problem by …
current drugs are commercially available, the ever-increasing drug resistance problem by …
The immune checkpoint CD96 defines a distinct lymphocyte phenotype and is highly expressed on tumor‐infiltrating T cells
A Lepletier, VP Lutzky, D Mittal… - Immunology and cell …, 2019 - Wiley Online Library
CD 96 has recently been shown to be a potent immune checkpoint molecule in mice, but a
similar role in humans is not known. In this study, we provide a detailed map of CD 96 …
similar role in humans is not known. In this study, we provide a detailed map of CD 96 …
Immune signature against Plasmodium falciparum antigens predicts clinical immunity in distinct malaria endemic communities
A large body of evidence supports the role of antibodies directed against the Plasmodium
spp. parasite in the development of naturally acquired immunity to malaria, however an …
spp. parasite in the development of naturally acquired immunity to malaria, however an …
Comparative analysis of the humoral immune response to the EBV proteome across EBV-related malignancies
Abstract Background: Epstein–Barr virus (EBV) is linked to multiple cancers, including
classical Hodgkin lymphoma (cHL), endemic Burkitt lymphoma (eBL), nasopharyngeal …
classical Hodgkin lymphoma (cHL), endemic Burkitt lymphoma (eBL), nasopharyngeal …
Deciphering host immunity to malaria using systems immunology
A century of conceptual and technological advances in infectious disease research has
changed the face of medicine. However, there remains a lack of effective interventions and a …
changed the face of medicine. However, there remains a lack of effective interventions and a …
Characterization of the humoral immune response to the EBV proteome in extranodal NK/T-cell lymphoma
Z Liu, YD Sarathkumara, JKC Chan, YL Kwong… - Scientific Reports, 2021 - nature.com
Extranodal natural killer/T-cell lymphoma (NKTCL) is an aggressive malignancy that has
been etiologically linked to Epstein-Barr virus (EBV) infection, with EBV gene transcripts …
been etiologically linked to Epstein-Barr virus (EBV) infection, with EBV gene transcripts …