Mass spectrometry imaging: a review of emerging advancements and future insights

AR Buchberger, K DeLaney, J Johnson… - Analytical …, 2017 - pmc.ncbi.nlm.nih.gov
Mass spectrometry imaging (MSI) is a powerful tool that enables untargeted investigations
into the spatial distribution of molecular species in a variety of samples. It has the capability …

Desorption electrospray ionization mass spectrometry imaging in discovery and development of novel therapies

T Soudah, A Zoabi, K Margulis - Mass Spectrometry Reviews, 2023 - Wiley Online Library
Desorption electrospray ionization mass spectrometry imaging (DESI‐MSI) is one of the
least specimen destructive ambient ionization mass spectrometry tissue imaging methods. It …

Review and perspectives on the applications of mass spectrometry imaging under ambient conditions

CJ Perez, AK Bagga, SS Prova… - Rapid …, 2019 - Wiley Online Library
Ambient mass spectrometry (AMS)‐based techniques are performed under ambient
conditions in which the ionization and desorption occur in the open environment allowing …

Direct infusion mass spectrometry for metabolomic phenotyping of diseases

R González-Domínguez, A Sayago… - Bioanalysis, 2017 - Taylor & Francis
Metabolomics based on direct mass spectrometry (MS) analysis, either by direct infusion or
flow injection of crude sample extracts, shows a great potential for metabolic fingerprinting …

Ambient mass spectrometry in metabolomics

CS Clendinen, ME Monge, FM Fernández - Analyst, 2017 - pubs.rsc.org
Since the introduction of desorption electrospray ionization (DESI) mass spectrometry (MS),
ambient MS methods have seen increased use in a variety of fields from health to food …

Recent advances in ambient mass spectrometry imaging

J Xue, Y Bai, H Liu - TrAC Trends in Analytical Chemistry, 2019 - Elsevier
The emerging ambient mass spectrometry imaging (MSI) enables to acquire molecular
images and information directly on the sample surface under the atmospheric environment …

Chemical analysis of the human brain by imaging mass spectrometry

A Ajith, Y Sthanikam, S Banerjee - Analyst, 2021 - pubs.rsc.org
Analysis of the chemical makeup of the brain enables a deeper understanding of several
neurological processes. Molecular imaging that deciphers the spatial distribution of …

Metabolomics and lipidomics analyses by 1H nuclear magnetic resonance of schizophrenia patient serum reveal potential peripheral biomarkers for diagnosis

L Tasic, JGM Pontes, MS Carvalho, G Cruz… - Schizophrenia …, 2017 - Elsevier
Using 1 H NMR-based metabolomics in association to chemometrics analysis, we analyzed
here the metabolic differences between schizophrenia patients (SCZ) compared to healthy …

[HTML][HTML] How can MSI enhance our understanding of ASO distribution?

L van der Vloet, PB Saint Hilaire, C Bouillod… - Drug Discovery …, 2024 - Elsevier
In the dynamic field of drug discovery and development, a comprehensive understanding of
drug absorption, distribution, metabolism, excretion, and toxicity is crucial. Mass …

Negatively charged gangliosides promote membrane association of amphipathic neurotransmitters

H Juhola, PA Postila, S Rissanen, F Lolicato… - Neuroscience, 2018 - Elsevier
Lipophilic neurotransmitters (NTs) such as dopamine are chemical messengers enabling
neurotransmission by adhering onto the extracellular surface of the post-synaptic membrane …