Unraveling the Potential Underlying Mechanisms of Mild Behavioral Impairment: Focusing on Amyloid and Tau Pathology

E Angelopoulou, A Bougea, A Hatzimanolis… - Cells, 2024 - pmc.ncbi.nlm.nih.gov
The emergence of sustained neuropsychiatric symptoms (NPS) among non-demented
individuals in later life, defined as mild behavioral impairment (MBI), is linked to a higher risk …

Roflumilast attenuates doxorubicin and cyclophosphamide combination-induced chemobrain in rats through modulation of NLRP3/ASC/caspase-1/GSDMD axis

G Eskander, SG Abdelhamid, SA Wahdan, SM Radwan - Life Sciences, 2025 - Elsevier
Aim The aim of this study is to investigate the neuroprotective effect of roflumilast, a
phosphodiesterase-4 (PDE-4) inhibitor on cognitive impairment induced by doxorubicin …

Causal effects of pediatric asthma on psychiatric disorders: a bidirectional Mendelian randomization study

Z Jiang, X Long, X Die, J Hou, Y Wang, Y Wang… - Journal of …, 2024 - Taylor & Francis
Background Previous studies have suggested a potential link between pediatric asthma and
psychiatric disorders. However, the causal relationship between pediatric asthma and …